Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620311 | 0.86 | CTSD (0.49) | SMN1; SMN2NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL14620353 | 0.81 | MTNR1A (0.44) | NPC1RAB9AKMT2APOLBMEN1 | |
| SCHEMBL14588760 | 0.78 | TSHR (0.48) | SMN1; SMN2ERCC5FEN1NPC1RAB9A | |
| SCHEMBL14620482 | 0.78 | TDP1 (0.44) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL3166061 | 0.73 | ERCC5 (0.62) | SMN1; SMN2ERCC5FEN1NPC1RAB9A | |
| SCHEMBL14620125 | 0.72 | MEN1 (0.47) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14620126 | 0.72 | CA1 (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL14620481 | 0.72 | PTGS2 (0.40) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14620480 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL17526417 | 0.69 | NPC1 (0.46) | SMN1; SMN2ERCC5FEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |