Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14620126 | 0.88 | CA1 (0.45) | ALDH1A1MAPTPKMHTTLMNA | |
| SCHEMBL14620480 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14620481 | 0.88 | PTGS2 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14620125 | 0.88 | MEN1 (0.47) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14620353 | 0.88 | MTNR1A (0.44) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL14620458 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14588759 | 0.78 | TDP1 (0.47) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL7731897 | 0.76 | TDP1 (0.42) | TDP1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL14620311 | 0.75 | CTSD (0.49) | KMT2ALMNASMN1; SMN2HPGDGAA | |
| SCHEMBL1201267 | 0.72 | NPC1 (0.62) | TDP1ALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169953-B2 | P-chiral phospholanes and phosphocyclic compounds and their use in asymmetric catalytic reactions | THE PENN STATE RESEARCH FOUNDATION (US) | 2007-01-30 | — | — | US | disclosed |