Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27576766 | 0.79 | THRB (0.40) | THRBTHRAKMT2ATYMSHPGD | |
| SCHEMBL146549 | 0.78 | KMT2A (0.38) | THRBKMT2AKEAP1TSHRHPGD | |
| SCHEMBL28703825 | 0.73 | THRB (0.38) | THRBTHRAKMT2AKEAP1HPGD | |
| SCHEMBL27881554 | 0.73 | ALDH1A1 (0.50) | THRBTHRAKMT2ATYMSTSHR | |
| SCHEMBL146450 | 0.72 | THRB (0.70) | THRBTHRATYMSTSHRHPGD | |
| SCHEMBL12300212 | 0.70 | — | — | |
| SCHEMBL27715812 | 0.69 | THRB (0.50) | THRBTHRATYMSCYP1A2MAPK1 | |
| SCHEMBL28511692 | 0.69 | KMT2A (0.49) | KMT2AKEAP1TSHRHPGDMEN1 | |
| SCHEMBL4595847 | 0.68 | THRB (0.74) | THRBTHRAKMT2ATSHRHPGD | |
| SCHEMBL819105 | 0.68 | THRB (0.56) | THRBTHRAMAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218463-A1 | RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-11-16 | — | — | WO | claimed |
| EP-2303331-B1 | OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME | ALCON INC (CH) | 2022-01-26 | — | — | EP | claimed |
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2018-12-06 | — | — | US | claimed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | claimed |
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | HITZ HANS (CH) | 2017-06-01 | — | — | US | claimed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| US-8980957-B2 | Methods for the preparation of biocompatible polymers, the polymers and their uses | CIS PHARMA AG (CH) | 2015-03-17 | — | — | US | claimed |
| US-20140242722-A1 | ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM | MEDTECH DETECT, LLC (US) | 2014-08-28 | — | — | US | claimed |
| WO-2014062910-A1 | SPIROPYRAN-BASED COLORIMETRIC DETECTION | MEDTECH DETECT, LLC (US) | 2014-04-24 | — | — | WO | claimed |
| US-20130158161-A1 | Polycarbonate Resin Composition with Mar Resistance and Scratch Resistance | CHEIL INDUSTRIES INC. (KR) | 2013-06-20 | — | — | US | claimed |
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |
| EP-1888660-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | Chemisches Institut Schaefer AG (CH) | 2008-02-20 | — | — | EP | claimed |
| US-7276544-B2 | Process for manufacturing intraocular lenses with blue light absorption characteristics | BAUSCH & LOMB INCORPORATED (US) | 2007-10-02 | — | — | US | claimed |
| WO-2006126095-A2 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 2006-11-30 | — | — | WO | claimed |
| EP-1664855-A1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB INCORPORATED (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005026787-A1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB INCORPORATED (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050055090-A1 | Process for manufacturing intraocular lenses with blue light absorption characteristics | BAUSCH HEALTH US, LLC | 2005-03-10 | — | — | US | claimed |
| US-6353069-B1 | INTRAOCULAR LENSES THAT HAVE HIGH REFRACTIVE INDEXES, ARE FLEXIBLE AND TRANSPARENT, CAN BE INSERTED INTO EYE THROUGH RELATIVELY SMALL INCISION, RECOVER ORIGINAL SHAPE AFTER HAVING BEEN INSERTED, AND ARE FREE OF GLISTENINGS | ALCON MANUFACTURING, LTD. | 2002-03-05 | — | — | US | claimed |
| EP-1080382-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | Alcon Laboratories, Inc. (US) | 2001-03-07 | — | — | EP | claimed |
| WO-1999053347-A1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON LABORATORIES, INC. (US) | 1999-10-21 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152335-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | THRB 4338/4885THRA 3671/4885KMT2A 3308/4885 |
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | THRB 4338/4885THRA 3671/4885KMT2A 3308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.