Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140955 | 0.75 | C1S (0.52) | SMN1; SMN2 | |
| SCHEMBL15660513 | 0.75 | KMT2A (0.47) | SMN1; SMN2 | |
| SCHEMBL4211209 | 0.73 | KMT2A (0.43) | SMN1; SMN2PRSS1PRSS2PRSS3 | |
| SCHEMBL17244472 | 0.66 | CA12 (0.52) | — | |
| SCHEMBL13140628 | 0.65 | ACHE (0.35) | — | |
| SCHEMBL9215228 | 0.65 | POLB (0.50) | SMN1; SMN2 | |
| SCHEMBL7950593 | 0.64 | ENPP2 (0.44) | — | |
| SCHEMBL24390454 | 0.63 | WDR5 (0.48) | SMN1; SMN2PRSS1PRSS2PRSS3 | |
| Water SCHEMBL27654065 | 0.63 | ALDH1A1 (0.50) | — | |
| SCHEMBL9220140 | 0.62 | ALDH1A1 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003525-A2 | CYCLIC ANILINO-PYRIDINOTRIAZINES AS GSK-3 INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-11 | — | — | WO | disclosed |