SCHEMBL14645952

SCHEMBL14645952

COc1c(C(C)(C)C)cc2c(c1-c1ccc(C(C)(C)C)cc1)CC(C)=C2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.33
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29906263 1.00 TDO2 (0.33) TDO2PTGS2
SCHEMBL14647324 0.88 PTGS2 (0.31) PTGS2
SCHEMBL3742137 0.88 PDE4B (0.39) PTGS2
SCHEMBL3740813 0.88 TDO2 (0.33) TDO2
SCHEMBL29992179 0.88 PTGS2 (0.31) PTGS2
SCHEMBL25334895 0.87 PTGS2 (0.38) PTGS2
SCHEMBL31179832 0.87 PTGS2 (0.38) PTGS2
SCHEMBL20165772 0.84 PTGS2 (0.32) PTGS2
SCHEMBL29873688 0.84 PTGS2 (0.32) PTGS2
SCHEMBL22687558 0.84 TDO2 (0.31) TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250145650-A1 C1 Symmetric 5-OMe-6-alkyl Substituted Metallocenes EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-05-08 US disclosed
CN-118891293-A C1 symmetrical 5-OMe-6-alkyl substituted metallocenes 埃克森美孚化学专利公司 2024-11-01 CN disclosed
US-11952481-B2 Heterophasic polypropylene composition with high flexibility and softness BOREALIS AG (AT) 2024-04-09 US disclosed
CN-111527140-B Heterophasic polypropylene composition with high flexibility and high softness 北欧化工公司 2023-11-17 CN disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
US-11807655-B2 Catalysts BOREALIS AG (AT) 2023-11-07 US disclosed
WO-2023150480-A1 C1 SYMMETRIC 5-OME-6-ALKYL SUBSTITUTED METALLOCENES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-10 WO disclosed
US-11702487-B2 Process for preparing propylene polymers BOREALIS AG (AT) 2023-07-18 US disclosed
US-11702487-B2 Process for preparing propylene polymers BOREALIS AG (AT) 2023-07-18 US disclosed
US-9630980-B2 Asymmetrical ligands BOREALIS AG (AT) 2017-04-25 US disclosed
US-20160024123-A1 Asymmetrical Ligands BOREALIS AG (AT) 2016-01-28 US disclosed
US-20160024123-A1 Asymmetrical Ligands BOREALIS AG (AT) 2016-01-28 US disclosed
US-9187583-B2 Catalysts BOREALIS AG (AT) 2015-11-17 US disclosed
US-9187583-B2 Catalysts BOREALIS AG (AT) 2015-11-17 US disclosed
US-20140221584-A1 CATALYSTS BOREALIS AG (AT) 2014-08-07 US disclosed
US-20140221584-A1 CATALYSTS BOREALIS AG (AT) 2014-08-07 US disclosed
EP-2729479-A1 CATALYSTS Borealis AG (AT) 2014-05-14 EP disclosed
WO-2013007650-A1 CATALYSTS BOREALIS AG (AT) 2013-01-17 WO disclosed
WO-2013007650-A1 CATALYSTS BOREALIS AG (AT) 2013-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250145650-A1 C1 Symmetric 5-OMe-6-alkyl Substituted Metallocenes RPS6, IMPA1, C1S TDO2 2679/4885PTGS2 1272/4885
US-11807655-B2 Catalysts SOD1, MT-CO2, MT-CO1 TDO2 2817/4885PTGS2 2491/4885
US-20160024123-A1 Asymmetrical Ligands CCRL2, AR, CCR2 TDO2 1604/4885PTGS2 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.