Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 3/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488774 | 0.84 | MET (0.46) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL487833 | 0.82 | JAK2 (0.58) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL487782 | 0.81 | MET (0.65) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30453255 | 0.81 | MET (0.65) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL488182 | 0.80 | RAB9A (0.58) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27630151 | 0.77 | MET (0.48) | RAB9AMETMAP4K3INPPL1JAK2 | |
| SCHEMBL30452968 | 0.77 | MAP4K4 (0.64) | METJAK2 | |
| SCHEMBL487734 | 0.77 | MAP4K4 (0.64) | METJAK2 | |
| SCHEMBL29118568 | 0.75 | ALDH1A1 (0.48) | RAB9APTGER1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29857597 | 0.74 | MET (0.48) | RAB9ACYP3A4METMAP4K3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603570-B1 | AMINOHETEROARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS | SUGEN INC (US) | 2013-01-23 | — | — | EP | disclosed |