Sugi Predict

Sugi Predict / Compounds / SCHEMBL14647828

SCHEMBL14647828

SCHEMBL14647828

C=C1OCc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 0.58
▸ MAOB P27338 1/20 0.58
▸ KMT2A Q03164 2/20 0.44
▸ ALDH1A1 P00352 8/20 0.41
▸ MAPT P10636 3/20 0.41
▸ RAB9A P51151 2/20 0.41
▸ KDM4E B2RXH2 5/20 0.39
▸ HPGD P15428 3/20 0.39
▸ CYP1A2 P05177 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ TYMS P04818 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ GAA P10253 3/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ HRH1 P35367 3/20 0.37
▸ KCNH2 Q12809 2/20 0.37
▸ HTR2B P41595 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15368900 0.78 MAOA (0.46) MAOAMAOBKMT2AALDH1A1MAPT
SCHEMBL19816896 0.77 CES1 (0.41) MAOAMAOBKMT2AALDH1A1KDM4E
SCHEMBL13616959 0.76 MAOB (0.52) MAOAMAOBKMT2AALDH1A1MAPT
Ethylene SCHEMBL10730104 0.74 MAOA (0.91) MAOAMAOBALDH1A1MAPTRAB9A
SCHEMBL6353583 0.73 MAOA (1.00) MAOAMAOBALDH1A1MAPTRAB9A
SCHEMBL132696 0.73 MAOB (0.60) MAOAMAOBKMT2AALDH1A1MAPT
SCHEMBL6903786 0.73 MAOA (1.00) MAOAMAOBALDH1A1MAPTRAB9A
SCHEMBL22284 0.73 MAOA (1.00) MAOAMAOBALDH1A1MAPTRAB9A
SCHEMBL29799860 0.73 MAOB (0.60) MAOAMAOBKMT2AALDH1A1MAPT
SCHEMBL11522370 0.73 MAOA (1.00) MAOAMAOBALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004236-B Method for synthesizing 3-methylenebenzofuran-1 (3H) -one compound 东华理工大学 2023-05-19 — — CN claimed
CN-115108964-A Phthalide derivative, preparation method and application 成都陈泷张科技有限责任公司 2022-09-27 — — CN claimed
CN-117043991-A Polyimide compound, negative electrode material for lithium ion secondary battery using same, negative electrode for lithium ion secondary battery, and lithium ion secondary battery 胜高科技股份有限公司 2023-11-10 — — CN disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
US-11697695-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2023-07-11 — — US disclosed
CN-113004236-B Method for synthesizing 3-methylenebenzofuran-1 (3H) -one compound 东华理工大学 2023-05-19 — — CN disclosed
CN-111770951-B Polyimide compound and molded article comprising same 胜高科技股份有限公司 2023-04-11 — — CN disclosed
CN-115108964-A Phthalide derivative, preparation method and application 成都陈泷张科技有限责任公司 2022-09-27 — — CN disclosed
CN-108947945-B 1, 3-dihydroisobenzofuran derivative and synthetic method and application thereof 曲阜师范大学 2022-08-02 — — CN disclosed
US-11186669-B2 Polymerizable composition and optically anisotropic body using same DIC CORPORATION (JP) 2021-11-30 — — US disclosed
US-20210284766-A1 RETARDATION FILM, ELLIPTICALLY POLARIZING PLATE, AND DISPLAY DEVICE INCLUDING THE SAME DIC CORPORATION (JP) 2021-09-16 — — US disclosed
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2017-10-26 — — US disclosed
WO-2017090418-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2017-06-01 — — WO disclosed
WO-2017015376-A1 CURABLE BENZOXAZINE COMPOSITIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2017-01-26 — — WO disclosed
US-9429568-B2 Silaanthracene as a red and near infrared sensor and a method to manufacture such a sensor BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY ON BEHALF OF SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) 2016-08-30 — — US disclosed
WO-2016114066-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME DIC株式会社 2016-07-21 — — WO disclosed
US-20150185209-A1 BIOLOGICALLY ACTIVE COMPLEX AND ITS PREPARATION SOUTHERN ILLINOIS UNIVERSITY CARBONDALE (US) 2015-07-02 — — US disclosed
WO-2014137717-A1 BENZOXAZINE CURABLE COMPOSITION CONTAINING POLYSULFONE-BASED TOUGHENERS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-09-12 — — WO disclosed
WO-2013122800-A1 MIXTURE OF BENZOXAZINE, EPOXY AND ANHYDRIDE HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-08-22 — — WO disclosed
WO-2013008437-A1 POLYIMIDE RESIN COMPOSITION AND LAMINATE INCLUDING SAME 三井化学株式会社 (JP) 2013-01-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150185209-A1 BIOLOGICALLY ACTIVE COMPLEX AND ITS PREPARATION PGLS, FOS, SPR MAOA 1080/4885MAOB 1536/4885KMT2A 2658/4885
US-20170306233-A1 POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY SMC4, PHOSPHO1, SMCHD1 MAOA 1780/4885MAOB 2390/4885KMT2A 3816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.