Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 10/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 10/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 10/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28174259 | 0.76 | BRS3 (0.41) | KDM4EALDH1A1KMT2A | |
| SCHEMBL14668260 | 0.76 | JMJD6 (0.48) | CHRNB2CHRNA4KDM4EALDH1A1MEN1 | |
| SCHEMBL14660197 | 0.73 | GRIK1 (0.33) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27483637 | 0.72 | CHRNB2 (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4MEN1 | |
| SCHEMBL27875069 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL2750343 | 0.71 | KMT2A (0.46) | GAAKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL19020351 | 0.70 | MGLL (0.51) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28165784 | 0.70 | ALDH1A1 (0.44) | KDM4EALDH1A1 | |
| SCHEMBL8766693 | 0.69 | DHFR (0.49) | — | |
| SCHEMBL29563076 | 0.68 | ALDH1A1 (0.57) | CHRNB4CHRNA3CHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013019442-A1 | PROCESS FOR THE PREPARATION OF 1,3-CYCLOHEXANEDIMETHANOL FROM ISOPHTHALIC ACID | EASTMAN CHEMICAL COMPANY (US) | 2013-02-07 | — | — | WO | claimed |
| US-8877984-B2 | Process for the preparation of 1,3-cyclohexanedimethanol from isophthalic acid | EASTMAN CHEMICAL COMPANY (US) | 2014-11-04 | — | — | US | disclosed |
| WO-2013019442-A1 | PROCESS FOR THE PREPARATION OF 1,3-CYCLOHEXANEDIMETHANOL FROM ISOPHTHALIC ACID | EASTMAN CHEMICAL COMPANY (US) | 2013-02-07 | — | — | WO | disclosed |
| US-20130030222-A1 | PROCESS FOR THE PREPARATION OF 1,3-CYCLOHEXANEDIMETHANOL FROM ISOPHTHALIC ACID | EASTMAN CHEMICAL COMPANY (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030222-A1 | PROCESS FOR THE PREPARATION OF 1,3-CYCLOHEXANEDIMETHANOL FROM ISOPHTHALIC ACID | HPD, CYP8B1, DHCR24 | CHRNB4 1135/4885CHRNA3 934/4885CHRNB2 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.