Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 5/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 3/20 | 0.32 |
| ▸ | MMP12 | P39900 | 3/20 | 0.32 |
| ▸ | RARB | P10826 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14439043 | 0.87 | — | — | |
| SCHEMBL15313430 | 0.85 | — | — | |
| SCHEMBL14701748 | 0.85 | PPARG (0.38) | TSHRALDH2RARBCTRCMAPT | |
| SCHEMBL14438727 | 0.81 | — | — | |
| SCHEMBL15313438 | 0.80 | MMP13 (0.32) | MMP13 | |
| SCHEMBL11967010 | 0.80 | GAA (0.42) | TSHRRARBMAPTPOLBAPEX1 | |
| SCHEMBL11967008 | 0.80 | GAA (0.42) | TSHRRARBMAPTPOLBAPEX1 | |
| SCHEMBL28355152 | 0.79 | THRB (0.45) | TSHRS1PR1 | |
| SCHEMBL11967011 | 0.79 | L3MBTL1 (0.41) | TSHRRARBMAPTPOLBAPEX1 | |
| SCHEMBL28678913 | 0.78 | POLB (0.48) | TSHRRARBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | SPIN2B, FLNB, LMNB2 | TSHR 3055/4885ALDH2 931/4885CYP1A2 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.