Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13908015 | 0.86 | KMT2A (0.38) | PPARGPPARAMEN1KMT2APTGES | |
| SCHEMBL11967010 | 0.85 | GAA (0.42) | PPARGPPARARARBTSHRL3MBTL1 | |
| SCHEMBL11967008 | 0.85 | GAA (0.42) | PPARGPPARARARBTSHRL3MBTL1 | |
| SCHEMBL8995717 | 0.85 | MGLL (0.42) | TSHRL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL14701740 | 0.85 | TSHR (0.33) | RARBTSHRALDH2MAPTCTRC | |
| SCHEMBL28355152 | 0.84 | THRB (0.45) | PPARGPPARATSHRMEN1KMT2A | |
| SCHEMBL11967011 | 0.84 | L3MBTL1 (0.41) | PPARGPPARARARBTSHRL3MBTL1 | |
| SCHEMBL13763464 | 0.83 | LMNA (0.41) | PPARGPPARATSHRMEN1KMT2A | |
| SCHEMBL28678913 | 0.83 | POLB (0.48) | RARBTSHRKMT2APOLBAPEX1 | |
| SCHEMBL11967012 | 0.80 | L3MBTL1 (0.42) | PPARGPPARATSHRL3MBTL1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | LOMOX LIMITED (GB) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130037752-A1 | ELECTROLUMINESCENT MATERIALS COMPRISING FLUORENE DERIVATIVES | SPIN2B, FLNB, LMNB2 | PPARG 1566/4885PPARA 680/4885RARB 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.