SCHEMBL25596263

SCHEMBL25596263

CCC(C)(C)C(=O)Oc1c(C)cc(C(C)(O)C(F)(F)F)cc1C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.34
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
TSHR P16473 2/20 0.32
VDR P11473 1/20 0.31
BRD4 O60885 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26078923 0.88 LMNA (0.39) LMNAKDM4EMAPK1
SCHEMBL12108423 0.84 ELANE (0.37) HSD11B1LMNAKDM4EMAPK1TSHR
SCHEMBL17068814 0.81 KDM4E (0.38) KDM4EMAPT
SCHEMBL9973369 0.79 ELANE (0.34) HSD11B1LMNA
SCHEMBL25968669 0.78 RIPK1 (0.33) VDR
SCHEMBL10115670 0.78 HSD11B1 (0.48) HSD11B1
SCHEMBL25596226 0.76 FAAH (0.39) HSD11B1KDM4ETSHR
SCHEMBL14015405 0.76 ELANE (0.35) KDM4E
SCHEMBL14701793 0.75 VDR (0.31) VDR
SCHEMBL19827499 0.73 BRD4 (0.31) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11681224-B2 Resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-06-20 US disclosed