Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | MEF2D | Q14814 | 4/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL1471009 | 0.83 | MAPT (0.56) | PRMT6MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1471422 | 0.80 | PRMT6 (0.53) | PRMT6HDAC4MEF2DAGXTMAPT | |
| SCHEMBL1471433 | 0.78 | HPGD (0.47) | MAPTKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL1471583 | 0.73 | HTR1A (0.35) | MAPTNPSR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30854955 | 0.69 | FABP1 (0.56) | PRMT6HDAC4MEF2DAGXTMAPT | |
| SCHEMBL30438836 | 0.69 | PRMT6 (0.63) | PRMT6HDAC4MEF2DAGXTMAPT | |
| SCHEMBL1036548 | 0.68 | PRMT6 (1.00) | PRMT6HDAC4MEF2DAGXTMAPT | |
| SCHEMBL5621913 | 0.66 | PRMT6 (0.97) | PRMT6HDAC4MEF2DAGXTMAPT | |
| SCHEMBL8305984 | 0.66 | RAB9A (0.53) | MAPTKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL1470949 | 0.66 | RAB9A (0.47) | MAPTKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915420-B2 | Aryl piperidine amides | JANSSEN PHARMACEUTICA NV (BE) | 2011-03-29 | — | — | US | disclosed |
| US-20080009521-A1 | Aryl Piperidine Amides | HUANG CHARLES Q | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009521-A1 | Aryl Piperidine Amides | BDNF, NTRK2, OPRL1 | PRMT6 1303/4885HDAC4 324/4885MEF2D 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.