Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | MIF | P14174 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14714715 | 0.78 | RAB9A (0.36) | RAB9ANPC1PKMKDM4EALDH1A1 | |
| SCHEMBL7860715 | 0.68 | KMT2A (0.42) | RAB9ANPC1PKMKDM4EALDH1A1 | |
| SCHEMBL31075128 | 0.67 | ALDH1A1 (0.32) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5188476 | 0.66 | RAB9A (0.40) | RAB9ANPC1PKMKDM4EALDH1A1 | |
| SCHEMBL26105549 | 0.65 | ESR1 (0.47) | RAB9ANPC1ALDH1A1HPGDMEN1 | |
| SCHEMBL28918336 | 0.65 | PNMT (0.43) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL28483707 | 0.64 | PNMT (0.57) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL31346823 | 0.64 | PNMT (0.57) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL8672207 | 0.64 | PNMT (0.53) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL456019 | 0.63 | PNMT (0.62) | RAB9ANPC1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051685-A | MODIFIED TRIPEPTIDE OF TYROSINE-D-ARGININE-PHENYLALANINE OR SALT WITH AMIDINO GROUP AT N-TERMINAL; ANALGESIC WHICH ACTS THROUGH ACTIONS OF OPIOID RECEPTORS; WITH SIDE EFFECT REDUCTION FOR USE IN TREATING CANCEROUS PAIN | DAIICHI PHARMACEUTICALS CO., LTD. (JP) | 2000-04-18 | — | — | US | disclosed |