Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716804 | 0.83 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1ALOX15LMNAHTR6 | |
| SCHEMBL648702 | 0.76 | BCAT2 (0.40) | L3MBTL1HTR6GAACA1CA2 | |
| SCHEMBL1682100 | 0.75 | GAA (0.50) | HTR6GAAITGAVCA1CA2 | |
| SCHEMBL13268425 | 0.74 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1ALOX15LMNAGAA | |
| SCHEMBL13900914 | 0.74 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1ALOX15LMNAGAA | |
| SCHEMBL9745397 | 0.73 | GAA (0.37) | HTR6GAAITGAVCA1CA2 | |
| SCHEMBL7430693 | 0.73 | GAA (0.37) | HTR6GAAITGAVCA1CA2 | |
| SCHEMBL15915761 | 0.73 | CA1 (0.58) | L3MBTL1ALDH1A1ALOX15CA1CA2 | |
| SCHEMBL12666580 | 0.73 | HSD11B1 (0.45) | L3MBTL1ALDH1A1ALOX5APFEN1HSD11B1 | |
| SCHEMBL13597685 | 0.73 | HSD11B1 (0.53) | L3MBTL1ALDH1A1LMNAGAAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10487099-B2 | Synthesis of hypervalent iodine reagents with dioxygen | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2019-11-26 | — | — | US | claimed |
| US-10974235-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200108380-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2020-04-09 | — | — | US | disclosed |
| US-10543481-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | TRUSTEES OF PRINCETON UNIVESITY (US) | 2020-01-28 | — | — | US | disclosed |
| US-10487099-B2 | Synthesis of hypervalent iodine reagents with dioxygen | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2019-11-26 | — | — | US | disclosed |
| US-20190002487-A1 | SYNTHESIS OF HYPERVALENT IODINE REAGENTS WITH DIOXYGEN | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2019-01-03 | — | — | US | disclosed |
| US-20180037526-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-02-08 | — | — | US | disclosed |
| US-9675923-B2 | Gas separations with redox-active metal-organic frameworks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-13 | — | — | US | disclosed |
| WO-2016130549-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-08-18 | — | — | WO | disclosed |
| US-20160158388-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2016-06-09 | — | — | US | disclosed |
| US-20130053585-A1 | GAS SEPARATIONS WITH REDOX-ACTIVE METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158388-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | L3MBTL1 4319/4885ALDH1A1 2126/4885ALOX15 3161/4885 |
| US-10543481-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | AFF2, CLTC, AFF4 | L3MBTL1 4319/4885ALDH1A1 2126/4885ALOX15 3161/4885 |
| US-20180037526-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | L3MBTL1 4319/4885ALDH1A1 2126/4885ALOX15 3161/4885 |
| US-20190002487-A1 | SYNTHESIS OF HYPERVALENT IODINE REAGENTS WITH DIOXYGEN | TPO, HAO2, OGFOD1 | L3MBTL1 3248/4885ALDH1A1 1554/4885ALOX15 1874/4885 |
| US-10974235-B2 | Targeted, metal-catalyzed fluorination of complex compounds with fluoride ion via decarboxylation | AFF2, CLTC, AFF4 | L3MBTL1 4319/4885ALDH1A1 2126/4885ALOX15 3161/4885 |
| US-20200108380-A1 | TARGETED, METAL-CATALYZED FLUORINATION OF COMPLEX COMPOUNDS WITH FLUORIDE ION VIA DECARBOXYLATION | AFF2, CLTC, AFF4 | L3MBTL1 4319/4885ALDH1A1 2126/4885ALOX15 3161/4885 |
| US-10487099-B2 | Synthesis of hypervalent iodine reagents with dioxygen | TPO, HAO2, OGFOD1 | L3MBTL1 3248/4885ALDH1A1 1554/4885ALOX15 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.