SCHEMBL1471830

SCHEMBL1471830

FC(F)=C(F)Oc1ccc(Br)cc1.[MgH2]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.37
LDHA P00338 1/20 0.36
CYP2A6 P11509 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
ALOX15 P16050 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
APP P05067 1/20 0.34
MGLL Q99685 1/20 0.34
CHRNA7 P36544 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1505790 0.98 CYP2A6 (0.38) MAPTLDHACYP2A6MEN1LMNA
SCHEMBL28280786 0.91 MAPK1 (0.39) MAPTLDHACYP2A6MEN1LMNA
SCHEMBL4530562 0.85 RAB9A (0.35) MAPTMEN1LMNARAB9AKMT2A
SCHEMBL28280789 0.83 APP (0.46) KMT2ACA1CA2CA9APP
SCHEMBL11956152 0.82 ALDH1A1 (0.32) MAPK1MGLLALDH1A1
SCHEMBL1505815 0.78 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL12833375 0.78 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL12833374 0.78 KMT2A (0.43) MAPTMEN1RAB9AKMT2ACA1
SCHEMBL8934991 0.78 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL1505923 0.76 MEN1 (0.48) MAPTMEN1LMNARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906526-B2 Electrolyte composition, solid electrolyte membrane, solid polymer fuel cell and manufacturing method for solid electrolyte membrane FUJITSU LIMITED (JP) 2014-12-09 US disclosed
US-20110070525-A1 ELECTROLYTE COMPOSITION, SOLID ELECTROLYTE MEMBRANE, SOLID POLYMER FUEL CELL AND MANUFACTURING METHOD FOR SOLID ELECTROLYTE MEMBRANE FUJITSU LIMITED (JP) 2011-03-24 US disclosed
US-7858215-B2 Electrolyte composition, solid electrolyte membrane, solid polymer fuel cell and manufacturing method for solid electrolyte membrane FUJITSU LIMITED (JP) 2010-12-28 US disclosed
US-20060216565-A1 Electrolyte composition, solid electrolyte membrane, solid polymer fuel cell and manufacturing method for solid electrolyte membrane FUJITSU LIMITED (JP) 2006-09-28 US disclosed
US-7037614-B1 Electrolyte composition, solid electrolyte membrane, solid polymer fuel cell and manufacturing method for solid electrolyte membrane FUJITSU LIMITED (JP) 2006-05-02 US disclosed