SCHEMBL1505790

SCHEMBL1505790

FC(F)=C(F)Oc1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.38
MAPT P10636 4/20 0.38
LDHA P00338 1/20 0.38
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
ALOX15 P16050 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 1/20 0.35
APP P05067 1/20 0.35
MGLL Q99685 1/20 0.35
CHRNA7 P36544 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1471830 0.98 MAPT (0.37) CYP2A6MAPTLDHAMEN1LMNA
SCHEMBL28280786 0.94 MAPK1 (0.39) CYP2A6MAPTLDHAMEN1LMNA
SCHEMBL4530562 0.87 RAB9A (0.35) MAPTMEN1LMNARAB9AKMT2A
SCHEMBL28280789 0.85 APP (0.46) KMT2ACA1CA2CA9APP
SCHEMBL11956152 0.84 ALDH1A1 (0.32) MAPK1MGLLALDH1A1
SCHEMBL1505815 0.80 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL8934991 0.80 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL12833375 0.80 KIF11 (0.39) MEN1LMNAMAPK1RAB9AKMT2A
SCHEMBL12833374 0.80 KMT2A (0.43) MAPTMEN1RAB9AKMT2ACA1
SCHEMBL1505923 0.78 MEN1 (0.48) MAPTMEN1LMNARAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371872-A Dampproof dustproof epoxy paint and preparation method thereof 江苏丰彩建材(集团)有限公司 2025-01-28 CN claimed
CN-119371872-B Dampproof dustproof epoxy paint and preparation method thereof 江苏丰彩建材(集团)有限公司 2025-11-14 CN disclosed
US-20250343325-A1 COMPOSITE SEPARATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2025-11-06 US disclosed
EP-4632934-A1 COMPOSITE SEPARATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Contemporary Amperex Technology Co., Limited (CN) 2025-10-15 EP disclosed
CN-119371872-A Dampproof dustproof epoxy paint and preparation method thereof 江苏丰彩建材(集团)有限公司 2025-01-28 CN disclosed
CN-119371872-A Dampproof dustproof epoxy paint and preparation method thereof 江苏丰彩建材(集团)有限公司 2025-01-28 CN disclosed
WO-2024216935-A1 COMPOSITE SEPARATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 宁德时代新能源科技股份有限公司 2024-10-24 WO disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
US-8815469-B2 Electrolyte, and fuel cell, Li secondary battery, secondary battery and primary battery using the electrolyte KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2014-08-26 US disclosed
WO-2005097843-A1 COMPOUND FOR OPTICAL MATERIALS AND METHODS OF FABRICATION GENERAL ELECTRIC COMPANY (US) 2005-10-20 WO disclosed
US-20050214479-A1 Compound for optical materials and methods of fabrication MOMENTIVE PERFORMANCE MATERIALS INC. 2005-09-29 US disclosed
EP-1573391-A2 SECOND ORDER NONLINEAR OPTICAL CHROMOPHORES, POLYMERS CONTAINING SAME, AND ELECTRO-OPTIC DEVICES THEREFROM Lumera Corporation (US) 2005-09-14 EP disclosed
US-20040266954-A1 Reversible crosslinking method for making an electro-optic polymer UNITED STATES AIR FORCE 2004-12-30 US disclosed
WO-2004065615-A2 REVERSIBLE CROSSLINKING METHOD FOR MAKING AN ELECTRO-OPTIC POLYMER UNIVERSITY OF WASHINGTON (US) 2004-08-05 WO disclosed
US-20040132960-A1 Polymers having pendant nonlinear optical chromophores and electro-optic devices therefrom LIGHTWAVE LOGIC, INC. 2004-07-08 US disclosed
WO-2004048927-A2 SECOND ORDER NONLINEAR OPTICAL CHROMOPHORES, POLYMERS CONTAINING SAME, AND ELECTRO-OPTIC DEVICES THEREFROM LUMERA CORPORATION (US) 2004-06-10 WO disclosed
EP-0727428-B1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHINETSU CHEMICAL CO (JP) 2001-06-06 EP disclosed
US-5665271-A Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-09-09 US disclosed
EP-0727428-A1 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050214479-A1 Compound for optical materials and methods of fabrication AFF2, AFF1, ELOVL6 CYP2A6 761/4885MAPT 1796/4885LDHA 4559/4885
US-20040132960-A1 Polymers having pendant nonlinear optical chromophores and electro-optic devices therefrom ETFA, PPOX, DDT CYP2A6 1788/4885MAPT 1285/4885LDHA 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.