Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720407 | 0.85 | CHRM3 (0.39) | CHRM3CHRM2CYP3A4ACHEVNN1 | |
| SCHEMBL14720297 | 0.76 | LIMK2 (0.48) | CHRM3CHRM2ACHEMEN1KMT2A | |
| SCHEMBL14720201 | 0.75 | HDAC1 (0.52) | CHRM3CHRM2KMT2A | |
| SCHEMBL14720757 | 0.74 | CHRM3 (0.44) | CHRM3CHRM2CYP3A4ACHEHTT | |
| SCHEMBL14720344 | 0.74 | OPRM1 (0.42) | ALDH1A1 | |
| SCHEMBL14731351 | 0.74 | FASN (0.50) | CYP3A4 | |
| SCHEMBL14720668 | 0.73 | OPRD1 (0.39) | CHRM3CHRM2KMT2A | |
| SCHEMBL14731350 | 0.73 | FASN (0.57) | — | |
| SCHEMBL2194496 | 0.72 | TSHR (0.70) | CHRM3HTTGAATSHRMEN1 | |
| SCHEMBL14720234 | 0.69 | GRIN2B (0.64) | CYP3A4VNN1CYP2D6CYP2C9GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |