SCHEMBL14725679

SCHEMBL14725679

Cn1cc2ccc3c(-c4cccc5c4sc4ccccc45)cc4cc5c(cc(-c6cccc7c6sc6ccccc67)c6ccc7cn(C)nc7c65)cc4c3c2n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.38
PAX8 Q06710 1/20 0.38
PARP14 Q460N5 1/20 0.38
ALOX5 P09917 1/20 0.38
PRKDC P78527 9/20 0.35
PIK3CD O00329 2/20 0.35
PIK3CB P42338 2/20 0.35
MAPT P10636 1/20 0.34
BRD4 O60885 1/20 0.34
PIK3CA P42336 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34
KCNH2 Q12809 1/20 0.34
BRDT Q58F21 1/20 0.34
HRH4 Q9H3N8 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PRNP P04156 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14725675 0.82 GPR3 (0.31) ALOX5MAPTALDH1A1HPGDRAB9A
SCHEMBL14725656 0.82 ACVRL1 (0.35) ALDH1A1HPGD
SCHEMBL14725676 0.79 ALOX5 (0.49) HTTPAX8PARP14ALOX5PRKDC
SCHEMBL14725633 0.77 ADORA3 (0.36) MAPTBRD4KDM4EALDH1A1HPGD
SCHEMBL14725672 0.77 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBHRH4
SCHEMBL14725649 0.76 CYP11B2 (0.41)
SCHEMBL14725661 0.75 KDM4E (0.35) MAPTATML3MBTL1KDM4EALDH1A1
SCHEMBL16307741 0.73 ALOX5 (0.51) HTTPAX8PARP14ALOX5PRKDC
SCHEMBL12927914 0.73 ALOX5 (0.54) HTTPAX8PARP14ALOX5PRKDC
SCHEMBL16307760 0.73 ALOX5 (0.46) HTTPAX8PARP14ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255084-B2 Heterocyclic compound and organic light-emitting device containing the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-02-09 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME TRPC1, TRPC4, TRPC6 HTT 401/4885PAX8 1291/4885PARP14 1505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.