SCHEMBL14732255

SCHEMBL14732255

O=c1c2ccccc2c2cc(-c3ccccc3)cc3c4cc(-c5ccccc5)ccc4n1c23

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.40
BRD4 O60885 2/20 0.40
TSPO P30536 1/20 0.39
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
FEN1 P39748 1/20 0.36
PLA2G2A P14555 1/20 0.36
PLA2G4A P47712 1/20 0.36
NR4A2 P43354 2/20 0.36
PIM1 P11309 1/20 0.35
NOTUM Q6P988 1/20 0.35
GLO1 Q04760 1/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20633762 1.00 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT
SCHEMBL14732257 0.98 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT
SCHEMBL20632499 0.97 MAOB (0.39) MAOBBRD4TSPOMEN1MAPT
SCHEMBL21636051 0.97 MAOB (0.42) MAOBBRD4TSPOMEN1MAPT
SCHEMBL15213890 0.97 MAOB (0.39) MAOBBRD4TSPOMEN1MAPT
SCHEMBL14732295 0.97 MAOB (0.39) MAOBBRD4TSPOMEN1MAPT
SCHEMBL21142693 0.94 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT
SCHEMBL21636126 0.94 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT
SCHEMBL21636032 0.94 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT
SCHEMBL22022438 0.94 MAOB (0.40) MAOBBRD4TSPOMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 US disclosed
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 US disclosed
US-11778907-B2 Composition for organic electronic devices MERCK PATENT GMBH (DE) 2023-10-03 US disclosed
US-11778907-B2 Composition for organic electronic devices MERCK PATENT GMBH (DE) 2023-10-03 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-11737352-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-08-22 US disclosed
US-20150065730-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
WO-2014194971-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-12-11 WO disclosed
WO-2014166586-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014166584-A1 ORGANIC ELECTROLUMINESCENT DEVICE WITH THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL MERCK PATENT GMBH (DE) 2014-10-16 WO disclosed
WO-2014094962-A2 METAL COMPLEXES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
WO-2014094963-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
WO-2013120577-A1 SPIROBIFLUORENE COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-22 WO disclosed
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 US disclosed
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 MAOB 2037/4885BRD4 932/4885TSPO 875/4885
US-11737352-B2 Materials for organic electroluminescent devices EPB41, EPB41L2, MCM4 MAOB 774/4885BRD4 902/4885TSPO 2032/4885
US-11877511-B2 Materials for organic light emitting devices DDT, ESD, ETFA MAOB 535/4885BRD4 199/4885TSPO 2332/4885
US-20130053555-A1 ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, PIEZO1, OR10J3 MAOB 951/4885BRD4 1222/4885TSPO 1056/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 MAOB 3740/4885BRD4 312/4885TSPO 284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.