Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARD | Q03181 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733349 | 1.00 | EPHX2 (0.43) | EPHX2KDM5AALDH1A1CES2CES1 | |
| SCHEMBL14733347 | 1.00 | EPHX2 (0.43) | EPHX2KDM5AALDH1A1CES2CES1 | |
| SCHEMBL11596281 | 0.76 | ALDH1A1 (0.39) | EPHX2KDM5AALDH1A1 | |
| SCHEMBL28177818 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG | |
| SCHEMBL7939776 | 0.74 | EPHX2 (0.62) | EPHX2KDM5AALDH1A1CES2CES1 | |
| SCHEMBL17914173 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG | |
| SCHEMBL2058434 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG | |
| SCHEMBL2058893 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG | |
| SCHEMBL2058928 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG | |
| SCHEMBL2058987 | 0.74 | ALDH1A1 (0.54) | EPHX2ALDH1A1CES2CES1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801231-B2 | Oral compositions and methods of use | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-10-31 | — | — | US | disclosed |
| US-11779446-B2 | Oral compositions and methods of use | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-10-10 | — | — | US | disclosed |
| US-11642199-B2 | Dental appliance with cosmetic therapeutic aqueous solution | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-05-09 | — | — | US | disclosed |
| US-8647608-B2 | Therapeutic dental composition and related methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-02-11 | — | — | US | disclosed |
| US-8552086-B2 | Dental compositions including organogelators, products, and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-10-08 | — | — | US | disclosed |
| US-20130109780-A1 | DENTAL COMPOSITIONS INLCUDING ORGANOGELATORS, PRODUCTS, AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130052146-A1 | THERAPEUTIC DENTAL COMPOSITION AND RELATED METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130052146-A1 | THERAPEUTIC DENTAL COMPOSITION AND RELATED METHODS | SLC10A1, GDI2, EBP | EPHX2 1906/4885KDM5A 2972/4885ALDH1A1 2486/4885 |
| US-20130109780-A1 | DENTAL COMPOSITIONS INLCUDING ORGANOGELATORS, PRODUCTS, AND METHODS | ILK, EPM2A, PDE6G | EPHX2 1602/4885KDM5A 2335/4885ALDH1A1 2232/4885 |
| US-11779446-B2 | Oral compositions and methods of use | PHOSPHO1, PWWP2B, PLCG2 | EPHX2 550/4885KDM5A 2623/4885ALDH1A1 4763/4885 |
| US-11801231-B2 | Oral compositions and methods of use | HRH2, HRH3, TAS2R42 | EPHX2 300/4885KDM5A 3528/4885ALDH1A1 2912/4885 |
| US-11642199-B2 | Dental appliance with cosmetic therapeutic aqueous solution | RARG, RARA, POLR1C | EPHX2 4144/4885KDM5A 3449/4885ALDH1A1 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.