Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1061439 | 0.98 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL8829058 | 0.95 | ALDH1A1 (0.52) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL27973164 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4534755 | 0.81 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Trifluoromethanesulfonic Acid SCHEMBL31321991 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL19302827 | 0.80 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL15843887 | 0.79 | TSHR (0.45) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL2869922 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL9451758 | 0.78 | TSHR (0.48) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL137143 | 0.78 | ZDHHC20 (0.50) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608571-B2 | Method for recovering crude oil from a subterranean formation utilizing a polyphosphate ester | RHODIA INC. (US) | 2009-10-27 | — | — | US | claimed |
| US-4511677-A | Ion exchange-active compositions consisting of water-soluble polyelectrolyte upon ion exchange functional substrate | PHILLIPS PETROLEUM COMPANY (US) | 1985-04-16 | — | — | US | claimed |
| US-4230608-A | Stable water-in-oil emulsions of cationically modified quaternized polyacrylamide and their method of preparation | NALCO CHEMICAL COMPANY (US) | 1980-10-28 | — | — | US | claimed |
| WO-2026105736-A1 | POLYVINYL ALCOHOL-BASED FILM | 三菱ケミカル株式会社 | 2026-05-21 | — | — | WO | disclosed |
| EP-4722199-A1 | AZOLE COMPOUND, METHOD FOR SYNTHESIZING SAID AZOLE COMPOUND, AND USE THEREOF | SHIKOKU CHEMICALS CORPORATION (JP) | 2026-04-08 | — | — | EP | disclosed |
| EP-4675646-A1 | RADIATION-SHIELDING COMPOSITION, COMPOSITION, AND COATING OR COATING MATERIAL | Mitsubishi Chemical Corporation (JP) | 2026-01-07 | — | — | EP | disclosed |
| EP-4674786-A1 | WATER-SOLUBLE FILM FOR LIQUID DETERGENT PACKAGE CAPSULE, AND LIQUID DETERGENT PACKAGE CAPSULE | Aicello Corporation (JP) | 2026-01-07 | — | — | EP | disclosed |
| EP-3925982-B1 | DIVERTING AGENT AND METHOD OF FILLING FRACTURE IN WELL USING THE SAME | MITSUBISHI CHEM CORP (JP) | 2025-11-26 | — | — | EP | disclosed |
| US-20250289782-A1 | THIOL COMPOUND AND USES THEREOF | SHIKOKU CHEMICALS CORPORATION (JP) | 2025-09-18 | — | — | US | disclosed |
| US-12410363-B2 | Diverting agent and method of filling fracture in well using same | MITSUBISHI CHEMICAL CORPORATION (JP) | 2025-09-09 | — | — | US | disclosed |
| EP-3901204-B1 | GREASE-RESISTANT FILM, GREASE-RESISTANT BASE MATERIAL, AND GREASE-RESISTANT PAPER | KURARAY CO (JP) | 2025-07-16 | — | — | EP | disclosed |
| US-5885720-A | Paper coating agent | KURARAY CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0799711-A1 | Paper coating agent | KURARAY CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5430090-A | Saponified polyvinyl acetate, hydroxy fatty acid, plasticizer | NIPPON GOHSEI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-07-04 | — | — | US | disclosed |
| US-4857621-A | Cationic polymeric stabilizers for oil-in-water emulsions | THE STANDARD OIL COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| US-4574885-A | ANIONIC POLYMERS ARE USED TO REDUCE THE ADSORPTION OF SURFACTANTS AND CATIONIC POLYMERS IN A FORMATION | PHILLIPS PETROLEUM COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0066332-B1 | AQUEOUS PHASE POLYMERIZATION OF WATER MISCIBLE MONOMERS | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |
| US-4511677-A | Ion exchange-active compositions consisting of water-soluble polyelectrolyte upon ion exchange functional substrate | PHILLIPS PETROLEUM COMPANY (US) | 1985-04-16 | — | — | US | disclosed |
| US-4395306-A | HYPOHALITE CROSSLINKING ETHYLENICALLY UNSATURATED CARBOXAMIDE POLYMER THICKENER; ROOF SHINGLES | THE DOW CHEMICAL COMPANY (US) | 1983-07-26 | — | — | US | disclosed |
| US-4230608-A | Stable water-in-oil emulsions of cationically modified quaternized polyacrylamide and their method of preparation | NALCO CHEMICAL COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250289782-A1 | THIOL COMPOUND AND USES THEREOF | TMT1A, TXN, CTH | ALDH1A1 227/4885TSHR 4643/4885MAPK1 4473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.