Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505035 | 0.82 | VCAM1 (0.55) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL29310309 | 0.81 | CYP19A1 (0.48) | VCAM1ALDH1A1LMNACYP19A1HTT | |
| SCHEMBL20299265 | 0.79 | VCAM1 (0.52) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL30202647 | 0.79 | VCAM1 (0.52) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL14744515 | 0.79 | VCAM1 (0.60) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL658767 | 0.79 | VCAM1 (0.52) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL18339775 | 0.79 | VCAM1 (0.47) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL7782406 | 0.76 | VCAM1 (0.55) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL26926562 | 0.76 | VCAM1 (0.47) | VCAM1XDHALDH1A1LMNACYP19A1 | |
| SCHEMBL361867 | 0.75 | VCAM1 (0.59) | VCAM1XDHALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | HANGZHOU YIRUI PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-11-20 | — | — | US | disclosed |
| EP-4538261-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | Hangzhou Yirui Pharmaceutical Technology Co., Ltd. (CN) | 2025-04-16 | — | — | EP | disclosed |
| CN-117229258-B | N-tetrazolyl aryl urea derivative and preparation method and application thereof | 杭州壹瑞医药科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-117229258-A | N-tetrazolyl aryl urea derivative and preparation method and application thereof | 杭州壹瑞医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023237015-A1 | N-TETRAZOLYL ARYL UREA DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | 杭州壹瑞医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-117209472-A | KIF18A inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-10-14 | — | — | US | disclosed |
| EP-3558972-A1 | TETRAZOLE CONTAINING COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2019-10-30 | — | — | EP | disclosed |
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-13 | — | — | US | disclosed |
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-13 | — | — | US | disclosed |
| WO-2018114783-A1 | TETRAZOLE CONTAINING COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-06-28 | — | — | WO | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317092-A1 | TETRAZOLE CONTAINING COMPOUNDS | TSLP, IL5, TRPA1 | VCAM1 1377/4885XDH 808/4885ALDH1A1 485/4885 |
| US-20190177284-A1 | TETRAZOLYL-CONTAINING CYCLOPROPANECARBOXAMIDES | GAP43, PSEN1, PSEN2 | VCAM1 3998/4885XDH 1234/4885ALDH1A1 1165/4885 |
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | HNMT, AANAT, CHRNA5 | VCAM1 3900/4885XDH 1162/4885ALDH1A1 440/4885 |
| US-20250353835-A1 | N-TETRAZOLYL ARYL UREA-BASED DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF | BDKRB1, BDKRB2, UTS2R | VCAM1 187/4885XDH 2018/4885ALDH1A1 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.