Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 3/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746798 | 0.89 | TLR2 (0.43) | AKR1C3AKR1C2TLR2TLR1TUBB4A | |
| SCHEMBL14746497 | 0.76 | RECQL (0.41) | TLR2TLR1RECQL | |
| SCHEMBL14744381 | 0.76 | GAA (0.49) | MAPTHTTLMNAPOLBSMN1; SMN2 | |
| SCHEMBL14746704 | 0.74 | LMNA (0.38) | AKR1C3AKR1C2TLR2TLR1RECQL | |
| SCHEMBL14746841 | 0.73 | PTGS2 (0.50) | AKR1C3AKR1C2MAPTPOLB | |
| SCHEMBL14744240 | 0.73 | HSPB1 (0.47) | AKR1C3AKR1C2TP53MAPTHTT | |
| SCHEMBL14746703 | 0.73 | SCN10A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14746593 | 0.72 | HSD17B10 (0.45) | AKR1C3AKR1C2MAPTLMNAPOLB | |
| SCHEMBL14746735 | 0.72 | RORC (0.72) | — | |
| SCHEMBL14744562 | 0.71 | AKR1C3 (0.44) | AKR1C3AKR1C2TP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |