Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746497 | 0.82 | RECQL (0.41) | TLR2TLR1RECQLL3MBTL1PTPRC | |
| SCHEMBL14744381 | 0.78 | GAA (0.49) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL14744240 | 0.75 | HSPB1 (0.47) | KCNN4AKR1C3AKR1C2PTPRCBCHE | |
| SCHEMBL14746593 | 0.74 | HSD17B10 (0.45) | LMNAAKR1C3AKR1C2PTPRCBCHE | |
| SCHEMBL14744328 | 0.74 | CYP19A1 (0.52) | AKR1C3AKR1C2PTPRCBCHEACHE | |
| SCHEMBL14746807 | 0.74 | AKR1C3 (0.46) | LMNASCN10ATLR2TLR1RECQL | |
| SCHEMBL14744310 | 0.74 | PTPRC (0.42) | KCNN4L3MBTL1AKR1C3AKR1C2PTPRC | |
| SCHEMBL14746823 | 0.73 | PTPRC (0.44) | TLR2TLR1L3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL16103384 | 0.73 | NOTUM (0.43) | KCNN4 | |
| SCHEMBL14746841 | 0.73 | PTGS2 (0.50) | AKR1C3AKR1C2PTPRCBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |