Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692431 | 0.80 | SMN1; SMN2 (0.52) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL4997154 | 0.74 | THRB (0.43) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL2825473 | 0.73 | GAA (0.56) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL5562998 | 0.72 | L3MBTL1 (0.51) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL966107 | 0.72 | THRB (0.65) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL3188989 | 0.72 | HSD11B1 (0.56) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL5806269 | 0.71 | LMNA (0.46) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL14382346 | 0.71 | GAA (0.41) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL8957767 | 0.71 | TSHR (0.51) | GAATHRBSMN1; SMN2LMNAMEN1 | |
| SCHEMBL28492217 | 0.71 | THRB (0.41) | GAATHRBSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9399196-B2 | Composite polyamide membrane derived from monomer including amine-reactive and phosphorous-containing functional groups | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-07-26 | — | — | US | disclosed |
| US-20140170314-A1 | COMPOSITE POLYAMIDE MEMBRANE DERIVED FROM MONOMER INCLUDING AMINE-REACTIVE AND PHOSPHOROUS-CONTAINING FUNCTIONAL GROUPS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-06-19 | — | — | US | disclosed |
| WO-2013032586-A1 | COMPOSITE POLYAMIDE MEMBRANE DERIVED FROM MONOMER INCLUDING AMINE-REACTIVE AND PHOSPHOROUS-CONTAINING FUNCTIONAL GROUPS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-03-07 | — | — | WO | disclosed |