SCHEMBL14760945

SCHEMBL14760945

C=Cc1ccc(O)c(CCl)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
GABRA1 P14867 3/20 0.41
GABRB2 P47870 3/20 0.41
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 3/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP3A4 P08684 2/20 0.36
HPGD P15428 2/20 0.36
BLM P54132 2/20 0.36
HIF1A Q16665 2/20 0.36
SLC22A1 O15245 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
HSP90AA1 P07900 1/20 0.36
HSPD1 P10809 1/20 0.36
HSPA5 P11021 1/20 0.36
IDO1 P14902 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14761059 0.85 TRPA1 (0.44) TRPA1GABRA1GABRB2ALDH1A1MEN1
SCHEMBL13899836 0.83 TRPA1 (0.50) TRPA1GABRA1GABRB2ALDH1A1MEN1
SCHEMBL30101971 0.82 TRPA1 (0.48) TRPA1GABRA1GABRB2ALDH1A1CYP3A4
SCHEMBL685704 0.82 TRPA1 (0.48) TRPA1GABRA1GABRB2ALDH1A1CYP3A4
SCHEMBL11073040 0.81 ALDH1A1 (0.43) TRPA1ALDH1A1MAPT
SCHEMBL685611 0.80 TRPA1 (0.52) TRPA1GABRA1GABRB2ALDH1A1HSP90AA1
SCHEMBL4613626 0.80 GABRA1 (0.66) TRPA1GABRA1GABRB2ALDH1A1MEN1
SCHEMBL9164890 0.80 PTGS2 (0.57) ALDH1A1MEN1MAPTKMT2ACYP3A4
SCHEMBL15524685 0.80 TRPA1 (0.47) TRPA1GABRA1GABRB2ALDH1A1MEN1
SCHEMBL29951702 0.80 PTGS2 (0.57) ALDH1A1MEN1MAPTKMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108864341-A Poly(4-hydroxystyrene) based epoxy resin, its synthesis and application 湖北固润科技股份有限公司 2018-11-23 CN disclosed
CN-108255018-A Include photoetching compositions poly(4-hydroxystyrene) based epoxy resin as film-forming resin 湖北固润科技股份有限公司 2018-07-06 CN disclosed
US-9618867-B2 Pigment dispersion and toner CANON KABUSHIKI KAISHA (JP) 2017-04-11 US disclosed
US-20160246200-A1 PIGMENT DISPERSION AND TONER CANON KABUSHIKI KAISHA (JP) 2016-08-25 US disclosed
EP-2753982-B1 TONER CANON KK (JP) 2016-03-23 EP disclosed
US-9223240-B2 Toner CANON KABUSHIKI KAISHA (JP) 2015-12-29 US disclosed
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140205943-A1 TONER CANON KABUSHIKI KAISHA (JP) 2014-07-24 US disclosed
CN-103782242-A Toner CANON KK 2014-05-07 CN disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
CN-102998924-A Toner CANON KK 2013-03-27 CN disclosed
US-20130065174-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 US disclosed
WO-2013035885-A1 TONER CANON KABUSHIKI KAISHA (JP) 2013-03-14 WO disclosed