Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | DRD4 | P21917 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763883 | 0.86 | NOTUM (0.32) | ALDH1A1NOTUM | |
| SCHEMBL14763526 | 0.71 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1HTR1ADRD2 | |
| SCHEMBL15952820 | 0.64 | BRD9 (0.33) | — | |
| SCHEMBL3789998 | 0.64 | ALDH1A1 (0.48) | ALDH1A1GABRA1GABRB2P2RX7 | |
| SCHEMBL5412834 | 0.62 | GABRA1 (0.44) | GABRA1GABRB2P2RX7 | |
| SCHEMBL10518257 | 0.62 | MAPT (0.57) | ALDH1A1 | |
| SCHEMBL91279 | 0.61 | PNMT (0.62) | ALDH1A1GABRA1GABRB2HTR1ADRD2 | |
| SCHEMBL91282 | 0.61 | — | — | |
| SCHEMBL30633058 | 0.61 | — | — | |
| SCHEMBL17033315 | 0.61 | KCNJ5 (0.44) | CRHBPCRHR2ALDH1A1P2RX7KCNJ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| WO-2013035650-A1 | METHOD FOR PRODUCING ALPHA - HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | HSD17B7, BCKDK, HSD11B1 | CRHBP 2450/4885CRHR2 2197/4885ALDH1A1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.