Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL14765272

C[n+]1ccc(-c2csc(S)n2)cc1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.37
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.32
PABPC1 P11940 1/20 0.32
APOBEC3A P31941 1/20 0.32
EIF4H Q15056 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
TERT O14746 1/20 0.32
RAB9A P51151 3/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
KCNH2 Q12809 3/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16552761 0.89 HPGD (0.38) KDM1ANPSR1ALDH1A1HPGDPABPC1
SCHEMBL1984060 0.84 PABPC1 (0.42) ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G
Bromide SCHEMBL14765198 0.83 PABPC1 (0.41) ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G
Hydrochloric Acid SCHEMBL14764903 0.83 PABPC1 (0.46) ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G
SCHEMBL16552862 0.82 TERT (0.50) KDM1ANPSR1ALDH1A1TERTRAB9A
SCHEMBL16552577 0.82 PABPC1 (0.38) ALDH1A1PABPC1APOBEC3AEIF4HAPOBEC3G
Trifluoromethanesulfonic Acid SCHEMBL3630137 0.68 KCNH2 (0.47) TERTKCNH2ACHE
SCHEMBL4183399 0.67 LTA4H (0.56) KDM1ANPSR1ALDH1A1RAB9AMEN1
SCHEMBL14063445 0.67 GAA (0.54) ALDH1A1HPGDRAB9ATSHRHTT
Trifluoromethanesulfonic Acid SCHEMBL30330519 0.66 KCNH2 (0.45) KCNH2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2753620-B1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL SANDOZ AG (CH) 2017-02-15 EP disclosed
US-9382278-B2 Process for preparing ceftaroline fosamil SANDOZ AG (CH) 2016-07-05 US disclosed
US-20160009745-A1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL SANDOZ AG (CH) 2016-01-14 US disclosed
US-9169239-B2 Process for preparing ceftaroline fosamil SANDOZ AG (CH) 2015-10-27 US disclosed
US-20150073138-A1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL SANDOZ AG (CH) 2015-03-12 US disclosed
WO-2013034718-A1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL SANDOZ AG (CH) 2013-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150073138-A1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL FOS, FOSB, CYP3A7 KDM1A 1428/4885NPSR1 3511/4885ALDH1A1 2709/4885
US-20160009745-A1 NOVEL PROCESS FOR PREPARING CEFTAROLINE FOSAMIL FOS, FOSB, CYP3A7 KDM1A 934/4885NPSR1 3546/4885ALDH1A1 1757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.