Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 5/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | ADH5 | P11766 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634115 | 0.90 | RARB (0.43) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL14768869 | 0.87 | ALDH1A1 (0.50) | HSD17B10RXRARXRBCA1CA2 | |
| SCHEMBL18504207 | 0.86 | HSD17B10 (0.49) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL16769640 | 0.85 | RXRA (0.49) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL12780511 | 0.84 | HSD17B10 (0.56) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL16749653 | 0.83 | RXRA (0.59) | RARBRXRARXRBRARGMAP4K4 | |
| SCHEMBL12535966 | 0.82 | RXRA (0.54) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL10260784 | 0.82 | RXRA (0.54) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL16769649 | 0.82 | RXRA (0.54) | RARBHSD17B10RXRARXRBCA1 | |
| SCHEMBL15132369 | 0.82 | RXRA (0.56) | RARBHSD17B10RXRARXRBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951095-B2 | Chromium metal organic frameworks and synthesis of metal organic frameworks | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-04-24 | — | — | US | disclosed |
| US-9724668-B2 | Iron metal organic framework materials | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | THE TEXAS A&M UNIVERSITY SYSTEM | 2017-02-23 | — | — | US | disclosed |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2016-12-01 | — | — | US | disclosed |
| US-9102691-B2 | Aluminum metal organic framework materials | TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-11 | — | — | US | disclosed |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | U.S. DEPARTMENT OF ENERGY | 2015-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050995-A1 | Chromium Metal Organic Frameworks and Synthesis of Metal Organic Frameworks | OXGR1, TFRC, PICALM | RARB 2639/4885HSD17B10 3807/4885RXRA 2502/4885 |
| US-20160346759-A1 | Iron Metal Organic Framework Materials | TFRC, FTH1, FECH | RARB 4562/4885HSD17B10 4292/4885RXRA 4751/4885 |
| US-20150152123-A1 | Aluminum Metal Organic Framework Materials | AS3MT, ORAI2, ORAI3 | RARB 4394/4885HSD17B10 3999/4885RXRA 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.