Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 2/20 | 0.56 |
| ▸ | ATG4B | Q9Y4P1 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL958239 | 0.81 | FBP1 (1.00) | FBP1MEN1KMT2ACA1CA2 | |
| SCHEMBL28523107 | 0.79 | LMNA (0.62) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL3234255 | 0.79 | ATG4B (0.68) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL22680776 | 0.79 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL10152517 | 0.79 | ATG4B (0.79) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL19512174 | 0.76 | RAB9A (0.67) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL6465664 | 0.75 | ALDH1A1 (0.66) | FBP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9720508 | 0.75 | CA1 (0.73) | FBP1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28519087 | 0.74 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9APKM | |
| SCHEMBL3234242 | 0.74 | ATG4B (0.67) | MEN1KMT2ANPC1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1860158-B1 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GMBH (DE) | 2013-12-04 | — | — | EP | disclosed |
| US-7914893-B2 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof | MERCK PATENT GMBH (DE) | 2011-03-29 | — | — | US | disclosed |
| US-20070275244-A1 | Particles | MERCK PATENT GMBH | 2007-11-29 | — | — | US | disclosed |
| EP-1860158-A2 | Particles comprising a substrate and an anion-binding layer | MERCK PATENT GmbH (DE) | 2007-11-28 | — | — | EP | disclosed |