Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802419 | 0.94 | NPC1 (0.56) | MAPTALDH1A1KDM4EHPGDF10 | |
| SCHEMBL3790093 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1KDM4EHPGDHDAC2 | |
| SCHEMBL24791968 | 0.82 | HDAC1 (0.60) | MAPTALDH1A1HDAC1HDAC2HDAC3 | |
| SCHEMBL14817822 | 0.80 | NPC1 (0.58) | MAPTALDH1A1KDM4EHPGDF10 | |
| SCHEMBL14802407 | 0.78 | MAPT (0.66) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL10605968 | 0.77 | GAA (0.66) | MAPTALDH1A1KDM4EHDAC1HDAC8 | |
| SCHEMBL6816201 | 0.77 | RAB9A (0.83) | MAPTALDH1A1KDM4EHDAC1HDAC2 | |
| SCHEMBL11462217 | 0.77 | RAB9A (0.83) | MAPTALDH1A1KDM4EHDAC1HDAC2 | |
| SCHEMBL3784057 | 0.77 | GAA (0.55) | ALDH1A1KDM4EHPGDHDAC1HDAC2 | |
| SCHEMBL12933399 | 0.77 | HDAC2 (0.87) | MAPTALDH1A1KDM4EHPGDF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220401590-A1 | COMPOUND OR SALT THEREOF | SHIZUOKA PREFECTURAL UNIVERSITY CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| US-9035057-B2 | Dihydroethidine analogues and uses thereof | WASHINGTON UNIVERSITY (US) | 2015-05-19 | — | — | US | disclosed |
| US-9035057-B2 | Dihydroethidine analogues and uses thereof | WASHINGTON UNIVERSITY (US) | 2015-05-19 | — | — | US | disclosed |
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | NOX4, QDPR, ROS1 | MAPT 2035/4885ALDH1A1 114/4885KDM4E 2642/4885 |
| US-20220401590-A1 | COMPOUND OR SALT THEREOF | NR3C2, NR3C1, NR1H3 | MAPT 3926/4885ALDH1A1 2164/4885KDM4E 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.