Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | CASP6 | P55212 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17669252 | 0.90 | MAPT (0.71) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL15801114 | 0.90 | MAPT (0.71) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL3028108 | 0.87 | MAPT (0.69) | MAPTALDH1A1KMT2ACASP6GFER | |
| SCHEMBL14802425 | 0.87 | GFER (0.67) | MAPTALDH1A1KMT2ACASP6GFER | |
| SCHEMBL4985313 | 0.86 | GFER (0.70) | MAPTALDH1A1KMT2ACASP6GFER | |
| SCHEMBL10876210 | 0.86 | GFER (0.65) | MAPTALDH1A1KMT2ACASP6GFER | |
| SCHEMBL1484133 | 0.86 | MAPT (0.67) | MAPTALDH1A1KMT2ACASP6GFER | |
| SCHEMBL1372140 | 0.85 | MAPT (0.66) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL27845814 | 0.84 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL336009 | 0.83 | NPC1 (0.65) | MAPTALDH1A1KMT2AGFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12391667-B2 | N-methyl, n-(6-(methoxy)pyridazin-3-yl) amine derivatives as Autotaxin (ATX) modulators for the treatment of inflammatory airway or fibrotic diseases | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-08-19 | — | — | US | disclosed |
| EP-4003978-B1 | N-METHYL, N-(6-(METHOXY)PYRIDAZIN-3-YL) AMINE DERIVATIVES AS AUTOTAXIN (ATX) MODULATORS FOR THE TREATMENT OF INFLAMMATORY AIRWAY OR FIBROTIC DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2024-05-01 | — | — | EP | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-20220281838-A1 | N-METHYL, N-(6-(METHOXY)PYRIDAZIN-3-YL) AMINE DERIVATIVES AS AUTOTAXIN (ATX) MODULATORS FOR THETREATMENT OF INFLAMMATORY AIRWAY OR FIBROTIC DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-09-08 | — | — | US | disclosed |
| US-20220281838-A1 | N-METHYL, N-(6-(METHOXY)PYRIDAZIN-3-YL) AMINE DERIVATIVES AS AUTOTAXIN (ATX) MODULATORS FOR THETREATMENT OF INFLAMMATORY AIRWAY OR FIBROTIC DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-09-08 | — | — | US | disclosed |
| WO-2021013833-A1 | N-METHYL, N-(6-(METHOXY)PYRIDAZIN-3-YL) AMINE DERIVATIVES AS AUTOTAXIN (ATX) MODULATORS FOR THE TREATMENT OF INFLAMMATORY AIRWAY OR FIBROTIC DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-01-28 | — | — | WO | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2017-03-02 | — | — | US | disclosed |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | SQUIBB & SONS LLC (US) | 2017-03-02 | — | — | US | disclosed |
| US-9499632-B2 | Human antibodies that bind CD22 and uses thereof | E.R. SQUIBB & SONS, L.L.C. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20090162372-A1 | FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE | MEDAREX, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| US-20090162372-A1 | FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE | MEDAREX, INC. (US) | 2009-06-25 | — | — | US | disclosed |
| WO-2009073533-A2 | ANTI-B7H4 MONOCLONAL ANTIBODY-DRUG CONJUGATE AND METHODS OF USE | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073524-A2 | CONJUGATES OF ANTI-RG-1 ANTIBODIES | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009073546-A2 | MONOCLONAL ANTIBODY PARTNER MOLECULE CONJUGATES DIRECTED TO PROTEIN TYROSINE KINASE 7 (PTK7) | MEDAREX, INC. (US) | 2009-06-11 | — | — | WO | disclosed |
| EP-2049508-A2 | N-HYDROXY-3-(4-{3-PHENYL-3-OXO-PROPENYL}-PHENYL)-ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER | DAC S.r.l. (IT) | 2009-04-22 | — | — | EP | disclosed |
| WO-2009026274-A1 | SITE-SPECIFIC ATTACHMENT OF DRUGS OR OTHER AGENTS TO ENGINEERED ANTIBODIES WITH C-TERMINAL EXTENSIONS | MEDAREX, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| WO-2007113249-A2 | N-HYDROXY-3-(4-{3-PHENYL-S-OXO-PROPENYL}-PHENYL)-ACRYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF CANCER | DAC S.R.L. (IT) | 2007-10-11 | — | — | WO | disclosed |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | NIPPON SODA CO., LTD. (JP) | 2006-11-02 | — | — | US | disclosed |
| EP-1650206-A1 | PHENYLAZOLE COMPOUNDS, PRODUCTION PROCESS, AND ANTIOXIDANTS | NIPPON SODA CO., LTD. (JP) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162372-A1 | FIBRONECTIN ED-B ANTIBODIES, CONJUGATES THEREOF, AND METHODS OF USE | FN1, EDNRB, EDF1 | MAPT 3372/4885ALDH1A1 4183/4885KMT2A 3018/4885 |
| US-20220281838-A1 | N-METHYL, N-(6-(METHOXY)PYRIDAZIN-3-YL) AMINE DERIVATIVES AS AUTOTAXIN (ATX) MODULATORS FOR THETREATMENT OF INFLAMMATORY AIRWAY OR FIBROTIC DISEASES | ENPP2, MYT1, INMT | MAPT 1693/4885ALDH1A1 3517/4885KMT2A 539/4885 |
| US-20170058031-A1 | HUMAN ANTIBODIES THAT BIND CD22 AND USES THEREOF | CD2BP2, CD22, CD2 | MAPT 3906/4885ALDH1A1 1167/4885KMT2A 1158/4885 |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | MAPT 442/4885ALDH1A1 4188/4885KMT2A 3168/4885 |
| US-20060247228-A1 | Phenylazole compounds production process and antioxidants | CBR1, CBR3, NOX3 | MAPT 2754/4885ALDH1A1 232/4885KMT2A 4566/4885 |
| US-12391667-B2 | N-methyl, n-(6-(methoxy)pyridazin-3-yl) amine derivatives as Autotaxin (ATX) modulators for the treatment of inflammatory airway or fibrotic diseases | ENPP2, MYT1, INMT | MAPT 1681/4885ALDH1A1 3760/4885KMT2A 552/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | MAPT 442/4885ALDH1A1 4188/4885KMT2A 3168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.