Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11743313 | 0.74 | CA2 (0.49) | CA2SLC22A12PTGS1PTGS2CA1 | |
| SCHEMBL14982011 | 0.72 | ALDH1A1 (0.38) | HSP90AA1 | |
| SCHEMBL4298702 | 0.72 | HSD17B10 (0.46) | — | |
| SCHEMBL2127567 | 0.68 | KEAP1 (0.61) | CA2SLC22A12PTGS1PTGS2 | |
| Phosphoric Acid SCHEMBL31173771 | 0.66 | PGAM1 (0.42) | CA2SLC22A12 | |
| SCHEMBL14703301 | 0.66 | CA2 (0.44) | CA2SLC22A12CA1 | |
| SCHEMBL1938502 | 0.65 | LMNA (0.46) | — | |
| SCHEMBL9564541 | 0.62 | GRIA1 (0.63) | CA2GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL19042419 | 0.61 | KEAP1 (0.57) | CA2CA1 | |
| SCHEMBL9094448 | 0.61 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729294-B2 | Process for producing optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| EP-2578566-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | Sumitomo Chemical Company Limited (JP) | 2013-04-10 | — | — | EP | disclosed |