Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 6/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | GLA | P06280 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | CASP7 | P55210 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | CFTR | P13569 | 3/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78381 | 0.85 | KDM4E (0.62) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL29543972 | 0.85 | KDM4E (0.62) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL4577829 | 0.82 | NR4A2 (0.56) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL29773857 | 0.82 | NR4A2 (0.56) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL25231136 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL30393581 | 0.82 | KDM4E (0.50) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL25458476 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL3839211 | 0.81 | NR4A2 (0.54) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL29400478 | 0.81 | GAA (0.70) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL2926607 | 0.81 | GAA (0.70) | ALDH1A1KDM4EGAAHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | SHANGHAI YIDIAN PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2026-05-28 | — | — | US | disclosed |
| EP-4735422-A1 | SUBSTITUTED CYCLIC COMPOUNDS AND METHODS OF TREATING PHENYLKETONURIA AND OTHER AMINO ACIDURIAS | Sanofi (FR) | 2026-05-06 | — | — | EP | disclosed |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | ORSOBIO, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| EP-4713095-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | Chengdu Anticancer Bioscience, Ltd. (CN) | 2026-03-25 | — | — | EP | disclosed |
| US-12528818-B2 | Compositions and methods for inhibition of RAS | LEIDOS BIOMEDICAL RESEARCH, INC. (US) | 2026-01-20 | — | — | US | disclosed |
| EP-3573972-B1 | RORGAMMA MODULATORS AND USES THEREOF | GENFIT (FR) | 2026-01-14 | — | — | EP | disclosed |
| US-12509462-B2 | 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives | BioVersys AG (CH) | 2025-12-30 | — | — | US | disclosed |
| US-20250376472-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | BioVersys AG (CH) | 2025-12-11 | — | — | US | disclosed |
| US-12454534-B2 | Pyrrolo[2,3-b]pyrazines as HPK1 inhibitor and the use thereof | BEONE MEDICINES I GMBH (CH) | 2025-10-28 | — | — | US | disclosed |
| US-20250325687-A1 | CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST | MABSOFT THERAPEUTICS SHANGHAI CO LTD (CN) | 2025-10-23 | — | — | US | disclosed |
| US-6323155-B1 | EXCELLENT LEVEL OF HERBICIDAL ACTIVITY TOGETHER WITH CROP TOLERANCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-11-27 | — | — | US | disclosed |
| EP-0944628-A1 | HETERO-BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS | American Cyanamid Company (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5908840-A | Hetero-biaryl-pyridoquinazolinone derivatives as anti-cancer agents | AMERICAN CYANAMID COMPANY (US) | 1999-06-01 | — | — | US | disclosed |
| EP-0674629-B1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1998-07-08 | — | — | EP | disclosed |
| WO-1998023617-A1 | HETERO-BIARYL-PYRIDOQUINAZOLINONE DERIVATIVES AS ANTI-CANCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1998-06-04 | — | — | WO | disclosed |
| EP-0674629-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014782-A1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-07-07 | — | — | WO | disclosed |
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376472-A1 | 3-(PHENYLSULFONYL)-[1,2,3]TRIAZOLO[1,5A]QUINAZOLIN-5(4H)-ONE DERIVATIVES | CUTA, IKZF3, STAT5A | ALDH1A1 3703/4885KDM4E 1563/4885GAA 4039/4885 |
| US-12454534-B2 | Pyrrolo[2,3-b]pyrazines as HPK1 inhibitor and the use thereof | PDXK, STK25, STK35 | ALDH1A1 3320/4885KDM4E 3177/4885GAA 1683/4885 |
| US-12606522-B2 | Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives | NR3C2, NR5A1, SRD5A2 | ALDH1A1 1507/4885KDM4E 3921/4885GAA 2559/4885 |
| US-20250325687-A1 | CONJUGATE COMPRISING TOLL-LIKE RECEPTOR AGONIST | TLR3, TLR7, TLR8 | ALDH1A1 3336/4885KDM4E 4052/4885GAA 867/4885 |
| US-12528818-B2 | Compositions and methods for inhibition of RAS | KRAS, NRAS, HRAS | ALDH1A1 2644/4885KDM4E 2945/4885GAA 3748/4885 |
| US-20260146037-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | JAK1, CTSZ, CTSL | ALDH1A1 4484/4885KDM4E 1597/4885GAA 2640/4885 |
| US-12509462-B2 | 3-(phenylsulfonyl)-[1,2,3]triazolo[1,5A]quinazolin-5(4H)-one derivatives | CUTA, OR10J3, CCR10 | ALDH1A1 1420/4885KDM4E 4357/4885GAA 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.