Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | CFTR | P13569 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543972 | 1.00 | KDM4E (0.62) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL148598 | 0.85 | ALDH1A1 (0.66) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL4577829 | 0.82 | NR4A2 (0.56) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL29773857 | 0.82 | NR4A2 (0.56) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL15284054 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL25231136 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL30393581 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL6168887 | 0.81 | GAA (0.66) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL7529190 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL861495 | 0.81 | PTPN2 (0.54) | ALDH1A1MAPTGAAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 984 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118978490-A | Synthesis process of 6- (2, 2-trifluoroethyl) -3H-quinazoline-4-ketone | 盐城嘉昊辰科技有限公司 | 2024-11-19 | — | — | CN | claimed |
| CN-118184526-A | Preparation method of 2-amino-3-chlorobenzoic acid methyl ester | 鹤壁市宝瑞德化工有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-116947634-A | Preparation method of 2, 5-dibromo methyl benzoate | 清源创新实验室 | 2023-10-27 | — | — | CN | claimed |
| CN-116082115-A | Synthesis method of 2-bromo-4-chloro-9, 9' -dimethylfluorene | 河南省科学院化学研究所有限公司 | 2023-05-09 | — | — | CN | claimed |
| CN-114394924-A | Organic two-state fluorescent molecular probe for viscosity detection and preparation method and application thereof | 南昌大学 | 2022-04-26 | — | — | CN | claimed |
| WO-2014143617-A1 | DEUTERIUM-ENRICHED TANAPROGET AND PROCESSES FOR ITS PREPARATION | TEVA WOMEN'S HEALTH, INC. (US) | 2014-09-18 | — | — | WO | claimed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | claimed |
| US-12637451-B2 | Amino quinazoline derivatives as P2X3 inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2026-05-26 | — | — | US | disclosed |
| CN-122059926-A | Heterocyclic degradation determinants for target protein degradation | C4医药公司 | 2026-05-19 | — | — | CN | disclosed |
| US-12605450-B2 | C3-carbon linked glutarimide Degronimers for target protein degradation | C4 THERAPEUTICS, INC. (US) | 2026-04-21 | — | — | US | disclosed |
| US-12600722-B2 | Tetracyclic compounds as DGK inhibitors | INCYTE CORPORATION (US) | 2026-04-14 | — | — | US | disclosed |
| US-20260092053-A1 | KHK INHIBITORS | GILEAD SCIENCES INC (US) | 2026-04-02 | — | — | US | disclosed |
| US-12577254-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | Signal Rx Pharmaceuticals, Inc. | 2026-03-17 | — | — | US | disclosed |
| US-4310677-A | Preparation of alkyl anthranilates | BASF AKTIENGESELLSCHAFT (DE) | 1982-01-12 | — | — | US | disclosed |
| US-4288362-A | Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-08 | — | — | US | disclosed |
| EP-0032672-A2 | Process for the preparation of alkylesters of anthranilic acid | BASF Aktiengesellschaft (DE) | 1981-07-29 | — | — | EP | disclosed |
| US-4260540-A | SPIN DYEING POLYACRYLONITRILE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| US-4246401-A | Axomethine pigments | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4225489-A | Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4014863-A | LACQUERS, PRINTING INKS, PAINTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605450-B2 | C3-carbon linked glutarimide Degronimers for target protein degradation | NEDD4, UBE3A, UBE3C | KDM4E 1603/4885ALDH1A1 3454/4885MAPT 4032/4885 |
| US-20260092053-A1 | KHK INHIBITORS | KHK, SLC5A2, HK1 | KDM4E 684/4885ALDH1A1 700/4885MAPT 1585/4885 |
| US-12577254-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | CHEK1, CDK1, CDK3 | KDM4E 1439/4885ALDH1A1 4453/4885MAPT 4233/4885 |
| US-12637451-B2 | Amino quinazoline derivatives as P2X3 inhibitors | P2RX3, P2RX1, P2RX7 | KDM4E 4583/4885ALDH1A1 1206/4885MAPT 4826/4885 |
| US-12600722-B2 | Tetracyclic compounds as DGK inhibitors | DGKB, DGKA, DGKK | KDM4E 4606/4885ALDH1A1 3804/4885MAPT 4838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.