Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1RN | P18510 | 5/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.61 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.59 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29498151 | 0.87 | BIRC2 (0.62) | ERAP2BIRC2ERAP1ALDH1A1THRB | |
| SCHEMBL29498141 | 0.84 | ALDH1A1 (0.59) | BIRC2ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL30906720 | 0.83 | IL1RN (0.63) | IL1RNERAP2BIRC2ERAP1ALDH1A1 | |
| SCHEMBL24345964 | 0.82 | BIRC2 (0.66) | BIRC2ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5812534 | 0.82 | LAP3 (0.55) | ANPEP | |
| SCHEMBL21570273 | 0.82 | LAP3 (0.55) | ANPEP | |
| SCHEMBL5812528 | 0.82 | LAP3 (0.55) | ANPEP | |
| SCHEMBL21570275 | 0.82 | LAP3 (0.55) | ANPEP | |
| SCHEMBL2632987 | 0.82 | REN (0.48) | IL1RNERAP2BIRC2ANPEP | |
| SCHEMBL464256 | 0.82 | MMP1 (0.53) | IL1RNERAP2BIRC2ERAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-2289888-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-7326799-B2 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2008-02-05 | — | — | US | disclosed |
| US-7326799-B2 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2008-02-05 | — | — | US | disclosed |
| US-20030153788-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU CORPORATION (JP) | 2003-08-14 | — | — | US | disclosed |
| EP-1295876-A1 | EPOXYCARBOXYLIC ACID AMIDES, AZIDES AND AMINO ALCOHOLS AND PROCESSES FOR PREPARATION OF ALPHA-KETO AMIDES BY USING THEM | SEIKAGAKU CORPORATION (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153788-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | REN, KDM8, CMA1 | IL1RN 875/4885ERAP2 392/4885BIRC2 2746/4885 |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | REN, CMA1, AKR1A1 | IL1RN 697/4885ERAP2 608/4885BIRC2 3032/4885 |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | AKR1C1, AKR1C4, AADAC | IL1RN 4009/4885ERAP2 1818/4885BIRC2 2076/4885 |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | CMA1, REN, TPSAB1 | IL1RN 526/4885ERAP2 334/4885BIRC2 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.