Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | LMNA | P02545 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | CASP7 | P55210 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14900390 | 0.86 | MAPT (0.59) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL14889979 | 0.85 | MAPT (0.82) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL14890182 | 0.82 | GAA (0.76) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL10925857 | 0.81 | ALDH1A1 (0.54) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL11626402 | 0.76 | LMNA (0.59) | MAPTLMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23958379 | 0.74 | CYP2D6 (0.92) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL10992668 | 0.74 | MAPT (0.50) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL27324835 | 0.74 | KCNH2 (0.72) | MAPTLMNAALDH1A1TSHRCASP1 | |
| SCHEMBL14890282 | 0.74 | NAMPT (0.56) | MAPTLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL26632300 | 0.74 | MAPK1 (0.68) | MAPTLMNAALDH1A1TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | claimed |
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | SERPINB1, TIMP3, MIF | MAPT 1521/4885LMNA 2227/4885ALDH1A1 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.