Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | OGA | O60502 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889778 | 0.96 | ALDH1A1 (0.60) | NAMPTALDH1A1KDM4ETHRBATM | |
| SCHEMBL14890067 | 0.90 | KMT2A (0.52) | NAMPTALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL14890137 | 0.86 | LMNA (0.52) | NAMPTALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL14890390 | 0.85 | ALDH1A1 (0.62) | NAMPTALDH1A1THRBKMT2ATSHR | |
| SCHEMBL14890277 | 0.85 | KMT2A (0.55) | NAMPTALDH1A1KDM4EKMT2ATSHR | |
| SCHEMBL14890178 | 0.83 | KMT2A (0.54) | NAMPTALDH1A1THRBKMT2ATSHR | |
| SCHEMBL14890097 | 0.83 | ALDH1A1 (0.58) | NAMPTALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL8556969 | 0.75 | REV1 (0.53) | ALDH1A1KDM4ETHRBATMKMT2A | |
| SCHEMBL12152008 | 0.74 | ALDH1A1 (0.44) | NAMPTALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL14890146 | 0.74 | MAPT (0.78) | ALDH1A1KMT2ATSHRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | claimed |
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | DREXEL UNIVERSITY | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109698-A1 | Small Molecule Inhibitors of Functions of the HIV-1 Matrix Protein | SERPINB1, TIMP3, MIF | NAMPT 345/4885ALDH1A1 3601/4885KDM4E 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.