Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018297 | 0.74 | GPR3 (0.39) | — | |
| SCHEMBL19495024 | 0.69 | GAA (0.38) | — | |
| SCHEMBL1491243 | 0.69 | — | — | |
| SCHEMBL21245236 | 0.63 | ITGB3 (0.42) | PIM1SIGMAR1HTR2A | |
| SCHEMBL6160924 | 0.58 | HTR1A (0.59) | SIGMAR1HTR2A | |
| SCHEMBL4872142 | 0.58 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL6170302 | 0.56 | SIGMAR1 (0.53) | SIGMAR1 | |
| SCHEMBL10313360 | 0.56 | PARP1 (0.31) | — | |
| SCHEMBL5068319 | 0.56 | ALDH1A1 (0.61) | SIGMAR1HTR2A | |
| SCHEMBL17390908 | 0.56 | HTR2A (0.89) | PIM1SIGMAR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403855-B1 | CARBAZOLE LINKED PYRROLO[2,1-C][1,4]BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2013-05-01 | — | — | EP | disclosed |