Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938410 | 0.90 | NR4A1 (0.56) | MRGPRX4NR4A2PPARASMN1; SMN2ACHE | |
| SCHEMBL3034601 | 0.81 | MRGPRX4 (0.61) | MRGPRX4NR4A2PPARATP53PKM | |
| SCHEMBL14938416 | 0.79 | ACHE (0.49) | ACHE | |
| SCHEMBL14938403 | 0.79 | PKM (0.55) | PKMACHE | |
| SCHEMBL22887457 | 0.76 | MRGPRX4 (0.74) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL22480958 | 0.75 | MRGPRX4 (1.00) | MRGPRX4NR4A2TP53PKMNFKB1 | |
| SCHEMBL13195446 | 0.75 | S1PR1 (0.56) | RAB9ANPC1S1PR1S1PR5 | |
| SCHEMBL339009 | 0.75 | NR4A2 (1.00) | MRGPRX4NR4A2SMN1; SMN2 | |
| SCHEMBL30207018 | 0.75 | NR4A2 (1.00) | MRGPRX4NR4A2SMN1; SMN2 | |
| SCHEMBL22480776 | 0.74 | MRGPRX4 (0.75) | MRGPRX4NR4A2TP53PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123243-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | CELTAXSYS, INC. | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123243-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | LTA4H, LTB4R, LTC4S | MRGPRX4 89/4885NR4A2 1526/4885PPARA 2040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.