Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939345 | 0.76 | MAPT (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14939995 | 0.75 | MAPT (0.45) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14939550 | 0.74 | KCNQ2 (0.44) | TSHRKDM4EALDH1A1MAPTCASP1 | |
| SCHEMBL14940088 | 0.69 | MAPT (0.49) | HRH4TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14939588 | 0.69 | ALDH1A1 (0.50) | TSHRSMN1; SMN2KDM4EALDH1A1MAPT | |
| SCHEMBL30476654 | 0.66 | HRH4 (0.51) | HRH4TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28357151 | 0.66 | HRH4 (0.51) | HRH4TSHRSMN1; SMN2KDM4ECASP1 | |
| SCHEMBL789776 | 0.66 | HRH4 (0.51) | HRH4TSHRSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14939704 | 0.65 | ADRA2C (0.48) | MAPTKMT2ADRD3 | |
| SCHEMBL14939375 | 0.65 | LMNA (0.46) | SMN1; SMN2ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |