Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944729 | 0.75 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL20343752 | 0.72 | ADORA2A (0.39) | — | |
| SCHEMBL14944658 | 0.72 | TLR7 (0.36) | ALDH1A1 | |
| SCHEMBL28852897 | 0.70 | HSP90AA1 (0.40) | ALDH1A1 | |
| SCHEMBL14944685 | 0.68 | TLR7 (0.33) | — | |
| SCHEMBL14944653 | 0.67 | DRD2 (0.31) | ALDH1A1 | |
| SCHEMBL19423858 | 0.67 | CCR5 (0.31) | ALDH1A1 | |
| SCHEMBL20343756 | 0.63 | TLR7 (0.41) | ALDH1A1 | |
| SCHEMBL4144591 | 0.63 | HPRT1 (0.50) | — | |
| SCHEMBL8165320 | 0.61 | BRD4 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |