Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PPID | Q08752 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | PPIG | Q13427 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184954 | 0.83 | GAA (0.68) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL3584747 | 0.83 | GAA (0.68) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL7870508 | 0.81 | GAA (0.77) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL6164664 | 0.81 | GAA (0.66) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL6245341 | 0.81 | GAA (0.66) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL22345261 | 0.80 | RECQL (0.61) | GAAALDH1A1TSHRMGAMSI | |
| SCHEMBL3553857 | 0.80 | TRPA1 (0.54) | GAAALDH1A1TRPA1MGAMSI | |
| SCHEMBL7247745 | 0.79 | GAA (0.63) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL3904057 | 0.79 | GAA (0.63) | GAAALDH1A1TRPA1TSHRMGAM | |
| SCHEMBL6759954 | 0.79 | GAA (0.63) | GAAALDH1A1TRPA1TSHRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552149-A | PDA modified cyclen coordination compound, and synthetic method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2025-03-04 | — | — | CN | claimed |
| CN-119552149-A | PDA modified cyclen coordination compound, and synthetic method and application thereof | 中国科学院精密测量科学与技术创新研究院 | 2025-03-04 | — | — | CN | disclosed |
| US-8648076-B2 | Cysteine protease inhibitors and their therapeutic applications | HYBRIGENICS SA (FR) | 2014-02-11 | — | — | US | disclosed |
| US-8648076-B2 | Cysteine protease inhibitors and their therapeutic applications | HYBRIGENICS SA (FR) | 2014-02-11 | — | — | US | disclosed |
| US-8648076-B2 | Cysteine protease inhibitors and their therapeutic applications | HYBRIGENICS SA (FR) | 2014-02-11 | — | — | US | disclosed |
| EP-2298362-B1 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING SPA (IT) | 2013-03-13 | — | — | EP | disclosed |
| EP-1469890-B1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2011-08-10 | — | — | EP | disclosed |
| EP-2298362-A1 | Responsive paramagnetic MRI contrast agents | Bracco Imaging S.p.A (IT) | 2011-03-23 | — | — | EP | disclosed |
| EP-1912954-B1 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2011-03-09 | — | — | EP | disclosed |
| US-20090215786-A1 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2009-08-27 | — | — | US | disclosed |
| US-20090215786-A1 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2009-08-27 | — | — | US | disclosed |
| US-20090215786-A1 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2009-08-27 | — | — | US | disclosed |
| US-7524483-B2 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.P.A. (IT) | 2009-04-28 | — | — | US | disclosed |
| EP-1912954-A2 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Hybrigenics S.A. (FR) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017758-A2 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2007-02-15 | — | — | WO | disclosed |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | BRACCO IMAGING S.P.A. (IT) | 2005-09-01 | — | — | US | disclosed |
| EP-1469890-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | Bracco Imaging S.p.A. (IT) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003063912-A1 | RESPONSIVE PARAMAGNETIC MRI CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2003-08-07 | — | — | WO | disclosed |
| EP-1331012-A1 | Responsive paramagnetic MRI contrast agents | BRACCO IMAGING S.p.A. (IT) | 2003-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215786-A1 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | SERPINB1, CTSF, CTSE | GAA 393/4885ALDH1A1 1453/4885TRPA1 2490/4885 |
| US-20050191243-A1 | Responsive paramagnetic mri contrast agents | MYT1, PRTN3, CECR2 | GAA 3443/4885ALDH1A1 4750/4885TRPA1 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.