Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL1496211

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O.[Na+]

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 known ✓ P47900 8/20 0.78
P2RY2 known ✓ P41231 4/20 0.78
ADORA1 known ✓ P30542 1/20 0.78
PDE4D known ✓ Q08499 1/20 0.78
PDE3A known ✓ Q14432 1/20 0.78
P2RX1 P51575 3/20 0.78
P2RX3 P56373 3/20 0.78
SRC P12931 2/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
P2RX2 Q9UBL9 2/20 0.78
P2RX4 Q99571 1/20 0.78
ALDH1A1 P00352 1/20 0.78
P2RY11 Q96G91 2/20 0.78
TRPM2 O94759 2/20 0.78
DNPH1 O43598 1/20 0.78
PRKAB2 O43741 1/20 0.78
LDHA P00338 1/20 0.78
ADRB2 P07550 1/20 0.78
FBP1 P09467 1/20 0.78
PRKAG1 P54619 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL30185881 1.00 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL2960692 0.98 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL31091233 0.97 P2RY1 (0.77) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL29653413 0.97 P2RY1 (0.77) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL8852600 0.97 P2RY1 (0.77) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Diphosphate SCHEMBL5498278 0.96 P2RY1 (0.80) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL29352529 0.95 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL28359 0.95 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Triphosphate SCHEMBL28357 0.95 P2RY1 (0.78) P2RY1P2RY2P2RX1P2RX3SRC
Adenosine Diphosphate SCHEMBL4406439 0.95 P2RY1 (0.80) P2RY1P2RY2P2RX1P2RX3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467715-A Process for simultaneously preparing D-glutamic acid and L-glutathione by multi-step enzyme method 珠海瑞德林生物有限公司 2024-01-30 CN claimed
CN-116410938-B Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2024-03-12 CN disclosed
CN-117467715-A Process for simultaneously preparing D-glutamic acid and L-glutathione by multi-step enzyme method 珠海瑞德林生物有限公司 2024-01-30 CN disclosed
CN-117384991-A Preparation method and application of high-bioactivity cyclic peptide 上海中翊日化有限公司 2024-01-12 CN disclosed
CN-113584105-B Method for preparing puromycin by enzyme method 深圳瑞德林生物技术有限公司 2023-10-20 CN disclosed
CN-116445429-A Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-07-18 CN disclosed
CN-116410938-A Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-07-11 CN disclosed
CN-116376853-A Beta-alanine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-07-04 CN disclosed
CN-115992103-A Enzyme mutant and preparation method of snake venom tripeptide 深圳瑞德林生物技术有限公司 2023-04-21 CN disclosed
CN-115820574-A Leucine ligase mutant and application thereof 深圳瑞德林生物技术有限公司 2023-03-21 CN disclosed
CN-115820578-A Mutant composition, fusion enzyme and preparation method of collagen tripeptide 深圳瑞德林生物技术有限公司 2023-03-21 CN disclosed
CN-115806946-A Preparation method of kyotorphin and derivatives thereof 深圳瑞德林生物技术有限公司 2023-03-17 CN disclosed
EP-2301555-B1 CREAMY O/W EMULSION COMPOSITION AND PRODUCTION PROCESS THEREOF OTSUKA PHARMA CO LTD (JP) 2016-02-17 EP disclosed
US-8492360-B2 Creamy O/W emulsion composition and production process thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110112045-A1 CREAMY O/W EMULSION COMPOSITION AND PRODUCTION PROCESS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-05-12 US disclosed
EP-2301555-A1 CREAM-LIKE O/W TYPE EMULSIFIED COMPOSITION AND METHOD FOR PRODUCING SAME Otsuka Pharmaceutical Co., Ltd. (JP) 2011-03-30 EP disclosed
EP-1342462-B1 O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME OTSUKA PHARMA CO LTD (JP) 2007-04-11 EP disclosed
US-6946436-B2 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2005-09-20 US disclosed
US-20040029761-A1 O/W emulsion composition and method of preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2004-02-12 US disclosed
EP-1342462-A1 O/W EMULSION COMPOSITION AND METHOD OF PREPARING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2003-09-10 EP disclosed