Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965802 | 0.90 | L3MBTL3 (0.43) | HSD11B1LMNAHPGDMGLLL3MBTL3 | |
| SCHEMBL14965608 | 0.83 | CHRM1 (0.48) | HSD11B1MGLLL3MBTL3L3MBTL1SCN9A | |
| SCHEMBL14965860 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EL3MBTL3L3MBTL1 | |
| SCHEMBL14965829 | 0.76 | ALDH1A1 (0.39) | LMNAALDH1A1KDM4EMAPT | |
| SCHEMBL14966212 | 0.75 | HSD11B1 (0.44) | HSD11B1ALDH1A1KDM4EMGLL | |
| SCHEMBL14965836 | 0.75 | MCHR1 (0.41) | ALDH1A1 | |
| SCHEMBL14965755 | 0.74 | EPHX2 (0.50) | POLBJAK2JAK1 | |
| SCHEMBL14965864 | 0.73 | ITGB3 (0.39) | LMNAALDH1A1KDM4E | |
| SCHEMBL14966196 | 0.73 | ALDH1A1 (0.49) | LMNAPOLBALDH1A1HPGDKDM4E | |
| SCHEMBL14965968 | 0.73 | LMNA (0.48) | LMNAALDH1A1KDM4ESERPINE1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |