Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965699 | 0.85 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL14966128 | 0.85 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14965999 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2MAPTLMNAKCNJ1 | |
| SCHEMBL14965773 | 0.82 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14966162 | 0.81 | CHRM1 (0.36) | SMN1; SMN2LMNACHRM1KCNH2 | |
| SCHEMBL14966317 | 0.81 | LOXL2 (0.42) | L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14965683 | 0.81 | DRD2 (0.43) | L3MBTL1ALDH1A1KCNH2KDM4E | |
| SCHEMBL14965508 | 0.81 | CAMKK2 (0.37) | SMN1; SMN2MAPTKCNJ1KCNH2 | |
| SCHEMBL14965918 | 0.81 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14965821 | 0.81 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2MAPTLMNAKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |