Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP4 | P49662 | 1/20 | 0.35 |
| ▸ | CASP5 | P51878 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965939 | 0.90 | PDE9A (0.39) | HTR7MEN1POLBKMT2ADHODH | |
| SCHEMBL14965655 | 0.90 | PDE4B (0.36) | HTR7MEN1POLBKMT2ADHODH | |
| SCHEMBL14971108 | 0.85 | ALDH1A1 (0.44) | FAAHMGLLKDM4EALDH1A1 | |
| SCHEMBL14965623 | 0.85 | CYP2A13 (0.48) | MEN1POLBKMT2AFAAHKDM4E | |
| SCHEMBL14965809 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2ADHODHKDM4EALDH1A1 | |
| SCHEMBL14965773 | 0.85 | L3MBTL1 (0.46) | MEN1POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL14965775 | 0.83 | L3MBTL1 (0.41) | MEN1POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL14971091 | 0.83 | DRD2 (0.44) | MEN1POLBKMT2AFAAHMGLL | |
| SCHEMBL14965813 | 0.79 | ALDH1A1 (0.53) | MEN1POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL14965823 | 0.78 | CLK2 (0.39) | KDM4EALDH1A1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |