Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK3 | P49761 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14965907 | 0.87 | TBK1 (0.37) | CHRM1L3MBTL1KCNJ1ALDH1A1LMNA | |
| SCHEMBL14965775 | 0.85 | L3MBTL1 (0.41) | CHRM1L3MBTL1KCNJ1ALDH1A1KDM4E | |
| SCHEMBL14971108 | 0.84 | ALDH1A1 (0.44) | L3MBTL1KCNJ1ALDH1A1KDM4ELMNA | |
| SCHEMBL14965513 | 0.83 | LSS (0.46) | DYRK1ACHRM1KCNJ1ALDH1A1LMNA | |
| SCHEMBL14965620 | 0.83 | ALDH1A1 (0.38) | CHRM1L3MBTL1KCNJ1ALDH1A1LMNA | |
| SCHEMBL14965550 | 0.83 | SLC2A1 (0.39) | DYRK1AKCNJ1ALDH1A1LMNAMAPT | |
| SCHEMBL14965746 | 0.82 | DRD2 (0.41) | CHRM1KCNJ1ALDH1A1LMNAMAPT | |
| SCHEMBL14965773 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KCNJ1ALDH1A1KDM4ELMNA | |
| SCHEMBL14965750 | 0.81 | CHKA (0.43) | CHRM1L3MBTL1KCNJ1ALDH1A1KDM4E | |
| SCHEMBL14965918 | 0.80 | ALDH1A1 (0.37) | CHRM1L3MBTL1KCNJ1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |