Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966123 | 0.82 | KMT2A (0.52) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14966005 | 0.81 | PKM (0.45) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14971161 | 0.79 | KMT2A (0.48) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14965417 | 0.79 | NAMPT (0.43) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14966076 | 0.79 | MEN1 (0.39) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14965857 | 0.77 | ENPP2 (0.36) | LMNAENPP2KMT2AMAPTALDH1A1 | |
| SCHEMBL14965582 | 0.75 | HSD17B10 (0.38) | LMNAKMT2ATDP1MAPTALDH1A1 | |
| SCHEMBL14966131 | 0.75 | DRD2 (0.49) | KMT2ATDP1ALDH1A1MEN1 | |
| SCHEMBL14965746 | 0.74 | DRD2 (0.41) | LMNAKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL14965730 | 0.73 | DRD2 (0.37) | LMNAKMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | claimed |
| WO-2013072903-A1 | NITROIMIDAZOXADIAZOCINE COMPOUNDS | ITHEMBA PHARMACEUTICALS (PROPRIETARY) LIMITED (ZA) | 2013-05-23 | — | — | WO | disclosed |