SCHEMBL14967734

SCHEMBL14967734

Cc1ccc(C2(C(=O)Oc3ccccc3)CO2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
POLB P06746 1/20 0.42
USP2 O75604 1/20 0.40
MAPT P10636 2/20 0.38
ALDH1A1 P00352 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ELANE P08246 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ATM Q13315 1/20 0.36
HSD11B1 P28845 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10415121 0.89 L3MBTL1 (0.43) L3MBTL1POLBMAPTALDH1A1KMT2A
SCHEMBL16109864 0.87 ALDH1A1 (0.44) L3MBTL1POLBUSP2MAPTALDH1A1
SCHEMBL14968340 0.79 CYP3A4 (0.43) LMNAL3MBTL1CYP2C9CYP2C19KMT2A
SCHEMBL9852819 0.77 L3MBTL1 (0.42) LMNAL3MBTL1POLBALDH1A1CYP2C19
SCHEMBL10414654 0.76 CES2 (0.47) LMNAL3MBTL1POLBMAPTALDH1A1
SCHEMBL5166279 0.76 OPRM1 (0.51) LMNAMAPTCYP1A2CYP2C9CYP2C19
SCHEMBL14967525 0.75 ABHD10 (0.40) LMNAL3MBTL1POLBALDH1A1NPSR1
SCHEMBL9774961 0.75 GPR119 (0.36) LMNAL3MBTL1CYP2C9CYP2C19KMT2A
SCHEMBL14967348 0.75 POLB (0.41) LMNAL3MBTL1POLBUSP2MAPT
SCHEMBL14967900 0.74 SCN1A (0.40) LMNAL3MBTL1POLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed